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Comprehensive evaluation and prediction of editing outcomes for near-PAMless adenine and cytosine base editors

Generation of near-PAMless base editorsTo leverage the expanded PAM compatibility offered by SpRY, our study utilized the BE4max-SpRY and ABEmax-SpRY, which incorporate SpRY in place of SpCas9,...

Data-driven discovery of chemotactic migration of bacteria via coordinate-invariant machine learning | BMC Bioinformatics

We constructed data-driven models for two different data sources (which, however correspond to the same general chemotaxis scenario): ...

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Comparative single-cell analyses of human and mouse kidney development

in Publications 30 mins ago 20 Views The kidney is a complex organ composed of various cell types, each playing a specific role in...

Single cell RNA-Seq reveals the cellular dynamics during degeneration and regeneration of brown adipose tissue

The prevalence of obesity worldwide has led to an increase in the risk of metabolic diseases and socio-economical burdens. Brown adipose tissue (BAT) has...

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