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Differential amino acid usage leads to ubiquitous edge effect in proteomes across domains of life that can be explained by amino acid secondary structure...

Proteomes differ among distant domains of lifeTwo competing hypotheses suggest that amino acid usage in proteomes differ or not among distant groups of living organisms. The lineage-specific...

Predicting transcriptional responses to novel chemical perturbations using deep generative model for drug discovery

PRnet: perturbation-conditioned deep generative model for transcriptional response predictionIn this paper, we formulate the transcriptional response prediction as a distribution generation problem conditioned on perturbations. Cells inherently...

Virtual resection evaluation based on sEEG propagation network for drug-resistant epilepsy

PatientsWe used two datasets: (1) Clinical data with 6 patients with 12 seizures from the neurosurgery department of Shanxi Provincial People’s Hospital; (2) HUP data with 10...

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Evidence stacks up for poisonous books containing toxic dyes

If you come across brightly colored, cloth-bound books from the Victorian era, you might want to handle them gently, or even steer clear altogether....

Researchers develop an instant version of trendy, golden turmeric milk

If you've visited a trendy café in the past few years, you might have noticed "golden" turmeric milk on the menu. Though recently advertised...

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