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Cusi, K. et al. Non-alcoholic fatty liver disease (NAFLD) prevalence and its metabolic associations in patients with type 1 diabetes and type 2 diabetes. Diabetes Obes. Metab....

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Predicting transcriptional responses to novel chemical perturbations using deep generative model for drug discovery

1_healthytip - 27 October 2024

PRnet: perturbation-conditioned deep generative model for transcriptional response predictionIn this paper, we formulate the transcriptional response prediction as a distribution generation problem conditioned on perturbations. Cells inherently...

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Virtual resection evaluation based on sEEG propagation network for drug-resistant epilepsy

1_healthytip - 27 October 2024

PatientsWe used two datasets: (1) Clinical data with 6 patients with 12 seizures from the neurosurgery department of Shanxi Provincial People’s Hospital; (2) HUP data with 10...

Vital Information

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Green-synthesis of silver nanoparticles AgNPs from Podocarpus macrophyllus for targeting GBM and LGG brain cancers via NOTCH2 gene interactions

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Data-driven discovery of chemotactic migration of bacteria via coordinate-invariant machine learning | BMC Bioinformatics

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Genomic landscape of adult testicular germ cell tumours in the 100,000 Genomes Project

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Profiling the transcriptomic age of single-cells in humans

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Metagenomic analysis of deep-sea bacterial communities in the Makassar and Lombok Straits

Economical impact

Optimal level of human intracranial theta activity for behavioral switching in the subthalamo-medio-prefrontal circuit

30 dead, dozens missing after torrential rain in central China

Novel gene writing technology enables all-RNA-mediated targeted gene integration in human cells

Olivar: towards automated variant aware primer design for multiplex tiled amplicon sequencing of pathogens

Cr dopant mediates hydroxyl spillover on RuO2 for high-efficiency proton exchange membrane electrolysis

Period blood could help diagnose diabetes and other illnesses

Facts

Acetylides from Alkynes, and The Substitution Reactions of Acetylides

20 August 2024

Spectroscopy and Synthesis Quizzes – Master Organic Chemistry

20 August 2024

SBTi’s Draft Chemical Sector Guidance Stifles Innovation and Fails to Support Industry Decarbonization Initiatives

15 July 2024

ACC Launches Ads Highlighting Sen. Roger Wicker

11 July 2024

Final Climate Disclosure Rules Include Key Change

11 July 2024

State of the Union Address: Current Regulatory Environment Misaligned with President Biden’s Policy Priorities

11 July 2024

Latest Articles

BIOCHEMICAL

Mechanistic insights on SSZ-13 zeolite in catalytic dimethyl ether carbonylation

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FITNESS MATTERS

Using AI to find the polymers of the future

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Nylon, Teflon, Kevlar. These are just a few familiar polymers -- large-molecule chemical compounds -- that have changed the world. From Teflon-coated frying pans...

BIOCHEMICAL

Support at work does not make ‘stuck’ employees less likely to retaliate, study finds

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FITNESS MATTERS

Heart data unlocks sleep secrets

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We know that quality sleep is as essential to survival as food and water. Yet, despite spending a third of our lives in slumber,...

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Enhancing COVID-19 forecasting precision through the integration of compartmental models, machine learning and variants

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We propose an integrated framework aimed at providing accurate and explainable predictions for epidemic spreads. Sybil combines a simple compartmental model with a machine...

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