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Predicting transcriptional responses to novel chemical perturbations using deep generative model for drug discovery

PRnet: perturbation-conditioned deep generative model for transcriptional response predictionIn this paper, we formulate the transcriptional response prediction as a distribution generation problem conditioned on perturbations. Cells inherently...

Differential amino acid usage leads to ubiquitous edge effect in proteomes across domains of life that can be explained by amino acid secondary structure...

Proteomes differ among distant domains of lifeTwo competing hypotheses suggest that amino acid usage in proteomes differ or not among distant groups of living organisms. The lineage-specific...

Virtual resection evaluation based on sEEG propagation network for drug-resistant epilepsy

PatientsWe used two datasets: (1) Clinical data with 6 patients with 12 seizures from the neurosurgery department of Shanxi Provincial People’s Hospital; (2) HUP data with 10...

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Why are triploid aspen common? – Macrosystems Ecology Laboratory

I just had a new paper come out (read in in the American Journal of Botany or download a PDF) exploring the question of...

Science community responds to Labour victory in UK general election | News

Science policy observers say that the UK’s research sector will be ‘breathing a sigh of relief’ following the Labour party’s landslide victory in the...

Band 8 Writing Answer for Chart

The chart below shows the value of one country’s exports in various categories during 2015 and 2016. The table shows the percentage...

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