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Could life survive in the plumes of Enceladus?

The Cassini spacecraft launched in 1997 on a 7-year journey to our second closest gas giant planet, Saturn, to...

RNA Sequencing reveals novel insights into chronic lymphocytic leukemia

RNA-sequencing has become a cornerstone in the study of gene expression, offering insights beyond mere mRNA transcript abundances. One area of increasing interest is alternative splicing, a...

Scientists Say: Kugelblitz

Kugelblitz (noun, “KOO-ghull-blitz”) A kugelblitz is a black hole made of pure light. Such objects are only theoretical. Some laws of physics suggest they should be able to...

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scBubbletree: computational approach for visualization of single cell RNA-seq data | BMC Bioinformatics

Study A: exploring sample of five cancer cell linesGenerating the bubbletreeWe know that dataset A contains a mixture of five cancer cell lines. Hence,...

Distinguishing word identity and sequence context in DNA language models | BMC Bioinformatics

The final source code is available as Sanabria Melissa, Hirsch Jonas, & Poetsch Anna R. (2023). Distinguishing word identity and sequence context in DNA...

Boundary-aware convolutional attention network for liver segmentation in ultrasound images

We have selected several excellent image segmentation algorithms for comparative experiments, including UNet9, RDeeplab42, TransUNet15, UNeXt43, LWBNAUNet44, and SegNeXt35. RDeeplab is an improved structure...

Integrative analysis of pan-cancer single-cell data reveals a tumor ecosystem subtype predicting immunotherapy response

ICI scRNA-Seq cohortsWe downloaded 5 ICI scRNA-Seq cohorts from the TISCH2 portal (http://tisch.comp-genomics.org/)11. The standard scRNA-Seq workflow were already completed by TISCH2 portal including...

Longitudinal genomic analysis of Neisseria gonorrhoeae transmission dynamics in Australia

Setting, patients and data sourcesIn Australia, all gonorrhoea cases are notified to public health authorities in each State or Territory. All N. gonorrhoeae isolated...

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