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Diagnostic precision in thyroid-associated ophthalmopathy using multi-center radiomics with 99mTc-DTPA SPECT/CT

PatientsThis retrospective study was performed in accordance with the Helsinki Declaration and approved by local Ethics Committee (approval no. UHCT22702). Adult patients (age ≥ 18 years) diagnosed with TAO...

QUIC-seq – quick ultra-affordable high-throughput convenient RNA sequencing

Understanding how genes function and regulate biological processes requires accurate measurement of transcript levels, which represent how much of a specific RNA molecule is present in a...

Chemoproteogenomic stratification of the missense variant cysteinome

Variant peptide identification enabled by MSFragger two-stage database search and false discovery rate (FDR) estimationTo enable chemoproteogenomic identification of SAAV-containing peptides, we established a customized proteogenomics pipeline...

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Non-invasive detection of hazardous materials with a thermal-to-epithermal neutron station: a feasibility study towards practical application

Bełdowski, J., Brenner, M. & Lehtonen, K. K. Contaminated by war: A brief history of sea-dumping of munitions. Mar. Environ. Res. 162, 105189. https://doi.org/10.1016/j.marenvres.2020.105189...

Amyloid transformations of phenol soluble modulin α1 in Staphylococcus aureus and their modulation deploying a prenylated chalcone

Isobavachalcone stably binds and interacts with the amyloid core of PSM α1The top docking clusters of PSM α1 bound to IBC, demonstrated the engagement...

8 must-see destinations for your (future) Mars vacation

Mars is a planet of vast contrasts — huge volcanoes, deep canyons, and craters that may or may not host running water. It will...

Covalent penicillin-protein conjugates elicit anti-drug antibodies that are clonally and functionally restricted

Ethics and permissionsAll experiments were conducted under approved licenses and protocols, consistent with national (as authorised by the Home Office of the United Kingdom)...

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