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Differential amino acid usage leads to ubiquitous edge effect in proteomes across domains of life that can be explained by amino acid secondary structure...

Proteomes differ among distant domains of lifeTwo competing hypotheses suggest that amino acid usage in proteomes differ or not among distant groups of living organisms. The lineage-specific...

Predicting transcriptional responses to novel chemical perturbations using deep generative model for drug discovery

PRnet: perturbation-conditioned deep generative model for transcriptional response predictionIn this paper, we formulate the transcriptional response prediction as a distribution generation problem conditioned on perturbations. Cells inherently...

Identification of diagnostic markers pyrodeath-related genes in non-alcoholic fatty liver disease based on machine learning and experiment validation

Cusi, K. et al. Non-alcoholic fatty liver disease (NAFLD) prevalence and its metabolic associations in patients with type 1 diabetes and type 2 diabetes. Diabetes Obes. Metab....

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Space photo of the week: Stunning sand dunes slash across Mars’ polar ice cap

What it is: Dunes on MarsWhere it is: Around Planum Boreum, the north polar ice cap on MarsWhen it was shared: Aug 6, 2024Why...

Heart attacks fell dramatically during the pandemic — and they’re still dropping

The COVID-19 pandemic heralded a 35% drop in hospital admissions for heart attacks in the U.S. — but even now, that rate is continuing...

Comparative analysis of feature selection techniques for COVID-19 dataset

4778 COVID-19 patients were included in the study, which examined 116 routine clinical, laboratory, and demographic features. The fatality rate in this cohort was...

Fossils from Greenland’s icy heart reveal it was a green tundra covered in flowers less than 1 million years ago

Today, nearly 98% of Greenland is covered in ice — but new research suggests it was virtually ice-free less than a million years ago.Over...

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