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Translation regulation by RNA stem-loops can reduce gene expression noise | BMC Bioinformatics

Model formulationFor the two-stage gene expression model (1), the probability (p_{m,n}(t)) of observing m mRNA and n protein molecules at time t satisfies the CME$$begin{aligned} begin{aligned} frac{textrm{d}}{textrm{d}...

SpliceTransformer predicts tissue-specific splicing linked to human diseases

Data representationThe input for the model is pre-mRNA sequences. The nucleotides A, C, G, and T are one-hot encoded, represented as , , , and , respectively....

Open letter from fraud sleuths raises concerns over research integrity at Scientific Reports | News

Scientific Reports, a journal published by Springer Nature, has been criticised for publishing fraudulent research in an open letter signed by many well-known experts in research fraud....

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Robot planning tool accounts for human carelessness

A new algorithm may make robots safer by making them more aware of human inattentiveness. In computerized simulations of packaging and assembly lines where humans...

Chemistry wordoku #057 | Puzzle

Solve this ‘wordoku’ in the same way as sudoku with letters instead of numbers (the nine letters once in each row, column and nine-square...

Thermoresponsive behavior of dual hydrophilic diblock copolymers prepared via organotellurium-mediated living radical polymerization

Bordat A, Boissenot T, Nicolas J, Tsapis N. Thermoresponsive polymer nanocarriers for biomedical applications. Adv Drug Deliv Rev. 2019;138:167–92.Article  CAS  ...

Zebrafish use surprising strategy to regrow spinal cord

Zebrafish are members of a rarefied group of vertebrates capable of fully healing a severed spinal cord. A clear understanding of how this regeneration...

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