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Overview of the Genomics England TGCT cohortAll TGCT tumour-normal sample pairs were processed through 100kGP bioinformatic somatic-variant analysis pipelines (tumour coverage: 95–122.7×, mean: 108.7×; normal: 31.3–62.6×, mean:...

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The prominent pervasive oncogenic role and tissue specific permissiveness of RAS gene mutations

1_healthytip - 26 October 2024

Data mining of CRISPR effect scores in DepMap showed prevalent difference in RAS genes between mutant lines vs. WT lines but also revealed drawbacks of individual assessment...

Vital Information

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Comprehensive evaluation and prediction of editing outcomes for near-PAMless adenine and cytosine base editors

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Will AI’s huge energy demands spur a nuclear renaissance?

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Self-supervised learning for accurately modelling hierarchical evolutionary patterns of cerebrovasculature

COACHING

The landscape of RNA binding proteins in mammalian spermatogenesis | Science

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Structural and free energy landscape analysis for the discovery of antiviral compounds targeting the cap-binding domain of influenza polymerase PB2

Economical impact

Associate Editor (Blog) – Functional Ecology – Functional Ecologists

The corona is weirdly hot: Parker Solar Probe rules out one explanation

Halloysite functionalized with dendritic moiety containing vitamin B1 hydrochloride as a bio-based catalyst for the synthesis of 5-hydroxymthylfurfural

Can tree species diversity make our forest more resilient to climate change?

Researchers discover prognostic lncRNAs in colorectal cancer using spatial transcriptomics

Soft electroactive polymer actuators based on regioregular/regiorandom-poly(3-hexylthiophene) blends with a nanofiber structure

Facts

Acetylides from Alkynes, and The Substitution Reactions of Acetylides

20 August 2024

Spectroscopy and Synthesis Quizzes – Master Organic Chemistry

20 August 2024

SBTi’s Draft Chemical Sector Guidance Stifles Innovation and Fails to Support Industry Decarbonization Initiatives

15 July 2024

ACC Launches Ads Highlighting Sen. Roger Wicker

11 July 2024

Final Climate Disclosure Rules Include Key Change

11 July 2024

State of the Union Address: Current Regulatory Environment Misaligned with President Biden’s Policy Priorities

11 July 2024

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Mars-bound payload on way to Florida for 1st launch of Blue Origin New Glenn

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Can global warming induce aridification in sub-tropical regions? Insights from geological global warming events

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Climate modeling projections suggest that anthropogenic global warming will induce intensified dry conditions in...

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Quantum data beamed alongside ‘classical’ data in a single fiber-optic connection for the 1st time

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Scientists have successfully transmitted quantum data and conventional data through a single optical fiber for the first time.The research demonstrates that quantum data in...

FITNESS MATTERS