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Exploring the role of different cell types on cortical folding in the developing human brain through computational modeling

Biological backgroundDuring human brain development, four fundamental cell types play an essential role, radial glial cells (RGCs), intermediate progenitor cells (IPCs), Outer radial glial cells (ORGCs), and...

Novel colon cancer subtype identifier based on RNA splicing

Researchers have discovered an alternative way to classify distinct types of colon cancer, making the information more valuable to patients and their doctors as they consider treatment. A...

Multi-layer graph attention neural networks for accurate drug-target interaction mapping

Multi-layer DTI networkGive a drug set (D={d_i}^{n_d}_{i=1}) and a target set (T={t_j}^{n_t}_{j=1}), the similarity between drugs (targets) can be assessed in various perspectives, which are represented by...

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Diarylation encodes precision for polyolefins

Diarylation encodes precision for polyolefins

Boy finds Roman-era gold military bracelet while walking dog in UK

While walking his dog with his mom, a 12-year-old boy in the U.K. made an unexpected discovery in a field — not a stick...

Study of pythons could lead to new therapies for heart disease, other illnesses

In the first 24 hours after a python devours its massive prey, its heart grows 25%, its cardiac tissue softens dramatically, and the organ...

Catalytic asymmetric synthesis of meta benzene isosteres

Salomen, L. M., Ellermann, M. & Diederich, F. Aromatic rings in chemical and biological recognition: energetics and structures. Angew. Chem. Int. Edn 50, 4808–4842 (2011). ...

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