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Quantifying constraint in the human mitochondrial genome

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Karczewski, K. J. et al. The mutational constraint spectrum quantified from variation in 141,456 humans. Nature 581, 434–443 (2020).Article  ADS  CAS  ...
HEALTHY

Widespread mutagenesis and chromosomal instability shape somatic genomes in systemic sclerosis

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Peoples, C., Medsger, T. A. Jr., Lucas, M., Rosario, B. L. & Feghali-Bostwick, C. A. Gender differences in systemic sclerosis: relationship to clinical features, serologic status and...
HEALTHY

The dynamics of blaTEM resistance genes in Salmonella Typhi

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Temporal and geographical distribution of Salmonella Typhi isolatesAll blaTEM harboring genomic sequences were downloaded, re-confirmed serovar Typhi using SISTR and classified as S. Typhi harboring blaTEM isolates...
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Holey basketballs! 3-D printing could be a game-changer

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3-D printing: A means of producing physical items — including toys, foods and even body parts — using a machine that takes instructions from...
BIOCHEMICAL

Promising new target discovered in pancreatic cancer could boost chemotherapy and reduce spread

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A molecule called nidogen-2...
ADVERTION

Ionic Equilibrium

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Ionic Equilibrium Contents: Degree of ionization Ostwald dilution law and its limitations pH scale Definition of pH and importance of pH scale, Relation between pH and concentration of H+...
WOLDING

Electrophilic As-functionalisation of σ-arsolido complexes

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The σ-arsolido complex ...
HEALTHY

Are we using the right statistics? – Naturally Speaking

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Are we using the right statistics? It is a contentious question in science. Statistics may seem like a hard, objective discipline, but there are...
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