Department of Genetics, Stanford University School of Medicine, Stanford, CA, USAJesse M. Engreitz, Benjamin C. Hitz, Anshul Kundaje, Andreas R. Gschwind, Dulguun Amgalan, Aradhana Aradhana, Sophia M. Arana, Michael C. Bassik, Julia R. Bauman, Asmita Bhattacharya, Xiangmeng Shawn Cai, Stephanie Conley, Benjamin R. Doughty, Peter P. Du, James A. Galante, Casey Gifford, William J. Greenleaf, Katherine Guo, Revant Gupta, Nimit Jain, Hank Jones, Helen Y. Kang, Sandy Klemm, Soumya Kundu, Yannick C. Lee-Yow, Roni Levin-Konigsberg, X. Rosa Ma, Georgi K. Marinov, Gabriella E. Martyn, Chloe V. McCreery, Eyal Metzl-Raz, Michael T. Montgomery, Chad Munger, Tri C. Nguyen, Kevin R. Roy, Jacob Schreiber, Maya U. Sheth, Lars M. Steinmetz, Jason Tan, Anthony Tan, Josh Tycko, Raeline C. Valbuena, Valeh Valiollah Pour Amiri, Mariëlle J. F. M. van Kooten, Alun Vaughan-Jackson, Anthony Venida, Fan Xia, David Yao, Tony Zeng, Ronghao Zhou, Livnat Jerby, Eran Kotler, Soumya Kundu, Stephen B. Montgomery, AkshatKumar Nigam, Jonathan Pritchard, Ivy Raine, Vivekanandan Ramalingam, Jacob M. Schreiber, J. Michael Cherry, Kalina Andreeva, Pedro R. Assis, Eric Douglass, Shengcheng Dong, Idan Gabdank, Keenan Graham, Otto Jolanki, Jennifer Jou, Meenakshi S. Kagda, Jin-Wook Lee, Mingjie Li, Khine Lin, Stuart R. Miyasato, Corinn Small, Emma Spragins, Forrest Y. Tanaka, Ian M. Whaling, Ingrid A. Youngworth & Cricket A. SloanBasic Science and Engineering Initiative, Stanford Children’s Health, Betty Irene Moore Children’s Heart Center, Stanford, CA, USAJesse M. Engreitz, Dulguun Amgalan, Xiangmeng Shawn Cai, Stephanie Conley, Casey Gifford, Katherine Guo, Hank Jones, Helen Y. Kang, Yannick C. Lee-Yow, X. Rosa Ma, Gabriella E. Martyn, Michael T. Montgomery, Kristy S. Mualim, Chad Munger, Tri C. Nguyen, Oriane M. Rubio, Maya U. Sheth, Jason Tan, Anthony Tan, Fan Xia, Tony Zeng & Ronghao ZhouThe Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Broad Institute of MIT and Harvard, Cambridge, MA, USAJesse M. Engreitz, Evelyn Jagoda, Glen Munson, Judhajeet Ray, Vasundhara Singh, Thouis R. Jones, Elisa Donnard, Maddie Murphy, Elizabeth Roberts & Susie SongGene Regulation Observatory, The Broad Institute of MIT and Harvard, Cambridge, MA, USAJesse M. Engreitz, Luca Pinello, Nina P. Farrell, Jason D. Buenrostro, Rachel E. Savage, Eugenio Mattei, Bradley E. Bernstein, Juliana Babu, Guillermo Barreto Corona, Kevin Dong, Fabiana M. Duarte, Neva C. Durand, Charles B. Epstein, Kaili Fan, Elizabeth Gaskell, Amelia W. Hall, Alexandra M. Ham, Mei K. Knudson, Noam Shoresh, Siddarth Wekhande, Cassandra M. White & Wang XiDepartment of Genetics, Washington University, St Louis, MO, USAHeather A. Lawson, Ting Wang, Changxu Fan, Daofeng Li, Xiaowen Ma, Juan Macias-Velasco, Kara Quaid, Wenjin Zhang, Guoyan Zhao & Xiaoyu ZhuoDepartments of Immunology and Computational and Systems Biology, University of Pittsburgh, Pittsburgh, PA, USAHarinder Singh, Jishnu Das, Marisa Abundis, Trirupa Chakraborty, Jingyu Fan, David R. Hall, Zarifeh H. Rarani, Swapnil Keshari, Nicholas A. Pease & Vivian F. YiDepartment of Genome Sciences, University of Washington, Seattle, WA, USALea M. Starita, Lara A. Muffley, Douglas M. Fowler, Jay Shendure, Vikram Agarwal, Florence M. Chardon, Nobuhiko Hamazaki, Connor Kubo, Jean-Benoît Lalanne, Beth Martin, Troy A. McDiarmid, Sam Regalado, Sabrina M. Best, Gabe Boyle, Silvia Casadei, Shawn Fayer, Audrey Hamm, Gail P. Jarvik, Abbye E. McEwen, Sriram Pendyala, Nicholas A. Popp, Mason Post, Nahum T. Smith, Malvika Tejura, Ziyu R. Wang, Melinda K. Wheelock, Ivan Woo, Brendan D. Zapp & John RayBrotman Baty Institute for Precision Medicine, Seattle, WA, USALea M. Starita, Douglas M. Fowler, Jay Shendure, Moez Dawood, Abbye E. McEwen & Jeremy StoneCecil H. and Ida Green Center for Reproductive Biology Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USAGary C. Hon, Nikhil V. Munshi, W. Lee Kraus, Daniel A. Armendariz, Hyung Bum Kim, Mpathi Z. Nzima, Anjana Sundarrajan, Lei Wang, Yihan Wang & Huan ZhaoDepartment of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX, USAGary C. Hon & W. Lee KrausDepartment of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, TX, USAGary C. HonDepartment of Medicine, University of California, San Diego, CA, USAHannah CarterDepartment of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Houston, TX, USANidhi Sahni, Deepa Bisht, Abhinav K. Jain, Babita Kaundal, Han Xu, Rongjie Fu, Wei He & Liang ZhangDepartment of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USANidhi SahniDepartment of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC, USATimothy E. Reddy, Alejandro Barrera, Andrew S. Allen, William H. Majoros, Keith Siklenka, Kari Strouse, C. David Page, Shannon Clarke, Richard W. Doty, Raluca Gordan, Kuei-Yueh Ko, Shengyu Li, Boyao Li & Alexander ThomsonDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USAXihong Lin, Eric Van Buren, Alkes Price, Xihao Li & Hufeng ZhouDepartment of Statistics, Harvard University, Cambridge, MA, USAXihong LinDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USAYun Li, Karen L. Mohlke, Michael I. Love, Stefanija Giric, Hyejung Won, Jessica L. Bell, K. Alaine Broadaway, Katherine N. Degner, Amy S. Etheridge, Beverly H. Koller, Won Mah, Jonathan D. Rosen, Sarah A. Schoenrock, Rachel A. Sharp & Xihao LiDepartment of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USAYun Li, Michael I. Love, Wancen Mu & Xihao LiDepartment of Internal Medicine, Division of Cardiology, University of Texas Southwestern Medical Center, Dallas, TX, USANikhil V. Munshi, Sean C. Goetsch & Sushama SivakumarDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USANikhil V. Munshi, Daniel A. Schmitz, Sushama Sivakumar, Jun Wu & Leqian YuEugene McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX, USANikhil V. Munshi, Maria H. Chahrour, Ashlesha Gogate, Lauretta El Hayek & Kiran KaurDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX, USAMaria H. ChahrourDepartment of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USAMaria H. ChahrourCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX, USAMaria H. ChahrourPeter O’Donnell Jr Brain Institute, University of Texas Southwestern Medical Center, Dallas, TX, USAMaria H. ChahrourDepartment of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USAAlan P. Boyle, Christopher P. Castro, Elysia Chou, Fan Feng, Yuanhao Huang, Linghua Jiang, Jie Liu, Ryan E. Mills, Weizhou Qian, Tingting Qin, Maureen A. Sartor, Rintsen N. Sherpa, Jinhao Wang, Yiqun Wang, Joshua D. Welch, Zhenhao Zhang & Nanxiang ZhaoDepartment of Human Genetics, University of Michigan, Ann Arbor, MI, USAAlan P. Boyle & Ryan E. MillsDepartment of Developmental and Cell Biology, UC Irvine, Irvine, CA, USAAli Mortazavi, Fairlie Reese, Dayeon Cheong, Ghassan Filibam, Kim Green, Grant MacGregor, Elisabeth Rebboah, Narges Rezaie & Ryan WeberCenter for Complex Biological Systems, UC Irvine, Irvine, CA, USAAli Mortazavi, Fairlie Reese, Shimako Kawauchi, Heidi Liang, Narges Rezaie & Jasmine SakrDepartment of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI, USAMark Craven, Yiyang Jin, Qiongshi Lu, Jiacheng Miao & Yuriy SverchkovDepartment of Pathology, Harvard Medical School, Boston, MA, USALuca Pinello, Logan J. Blaine, Eric Che, Nahye Kim, Emily M. King, Benjamin P. Kleinstiver, Zhijian Li, Zain M. Patel & Jayoung RyuMcDonnell Genome Institute, Washington University School of Medicine, St Louis, MO, USATing Wang, Sarah Cody, Eddie Belter, Lucinda Fulton, Tina Lindsay & Chad TomlinsonDepartment of Computer Science, Stanford University School of Medicine, Stanford, CA, USAAnshul Kundaje, Surag Nair, Austin T. Wang, Ziwei Chen, Soumya Kundu, Anusri Pampari, Jason Tan, Soumya Kundu, AkshatKumar Nigam, Aman Patel, Arpita Singhal & Austin T. WangDepartment of Biochemistry and Molecular Genetics, Feinberg School of Medicine Northwestern University, Chicago, IL, USAFeng Yue, Xintong Chen, Yu Luan, Huijue Lyu & Juan WangRobert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, USAFeng YueDivision of Genome Sciences, National Human Genome Research Institute (NHGRI), National Institutes of Health (NIH), Bethesda, MD, USAMichael J. Pazin, Stephanie Calluori, Daniel A. Gilchrist, Carolyn M. Hutter, Stephanie A. Morris & Ella K. SamerComputational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USAKushal K. Dey, Christina S. Leslie, Thahmina A. Ali, Kushal K. Dey, Preethi K. Periyakoil, Vianne R. Gao, Norman M. Thomas, Kaden M. Southard, Rico C. Ardy, Kushal K. Dey & Thahmina A. AliDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USAAlkes Price & Arun DurvasulaInstitute of Human Genetics, University Medical Center Schleswig-Holstein, University of Lübeck, Lübeck, GermanyMartin Kircher, Pia Keukeleire & Thorben MaassExploratory Diagnostic Sciences, Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin, GermanyMartin Kircher, Max Schubach, Theofilos Chalkiadakis & Pyaree M. DashComputational Biology Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA, USAJian MaKhoury College of Computer Sciences, Northeastern University, Boston, MA, USAPredrag Radivojac, Shantanu Jain, Daniel Zeiberg, M. Clara De Paolis Kaluza & Michelle VelyunskiyDepartment of Pathology and Laboratory Medicine, University of California Los Angeles, Los Angeles, CA, USABrunilda BalliuDepartment of Computational Medicine, University of California Los Angeles, Los Angeles, CA, USABrunilda Balliu & Jason ErnstDepartment of Biostatistics, University of California Los Angeles, Los Angeles, CA, USABrunilda BalliuDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USABrian A. Williams, Ingileif Hallgrimsdottir, Sina Booeshaghi, Lior Pachter, Barbara J. Wold, Charlene Kim, Rebekah Loving, Laura Luebbert, Angel G. Merchan, Delaney K. Sullivan, Diane Trout & Sean UpchurchDevelopmental Biology Program, Sloan Kettering Institute, New York, NY, USADanwei Huangfu, Anna-Katerina Hadjantonakis, Sharon Adeniyi, Hyein Cho, Rachel A. Glenn, David Godovich, Nan Hu, Svetlana Jovanic, Renhe Luo, Thomas Vierbuchen, Xianming Wang, Breanna Williams, Jielin Yan & Dapeng YangCenter for Stem Cell Biology, Sloan Kettering Institute for Cancer Research, New York, NY, USADanwei Huangfu, Anna-Katerina Hadjantonakis, Sharon Adeniyi, Hyein Cho, Rachel A. Glenn, David Godovich, Nan Hu, Svetlana Jovanic, Renhe Luo, Thomas Vierbuchen, Xianming Wang, Breanna Williams, Jielin Yan & Dapeng YangDivision of Cardiovascular Medicine, School of Medicine, Stanford University, Stanford, USAChong Y. Park, Thomas Quertermous, Evelyn Jagoda, Ramen Kundu, Daniel Y. Li, Joao P. Monteiro, Trieu Nguyen, Brian T. Palmisano, Markus Ramste, Gavin Schnitzler, Disha Sharma, Huitong Shi, Chad S. Weldy, Matthew D. Worssam, Quanyi Zhao, Rajat Gupta, Shi Fang & Vivian Lee-KimCenter for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USAMichael A. Calderwood, Marc Vidal, Georges Coppin, Tong Hao, David E. Hill, Florent Laval, Kerstin Spirohn-Fitzgerald, Maxime Tixhon, Anupama Yadav & Zhipeng YangDepartment of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USAMichael A. Calderwood, Marc Vidal, Georges Coppin, Tong Hao, David E. Hill, Florent Laval, Kerstin Spirohn-Fitzgerald, Maxime Tixhon, Anupama Yadav & Zhipeng YangDepartment of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USAMichael A. Calderwood, Georges Coppin, Tong Hao, David E. Hill, Florent Laval, Maxime Tixhon, Anupama Yadav, Zhipeng Yang & Bradley E. BernsteinDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, USALucas Ferreira, Evan Koch, Shamil Sunyaev, Logan J. Blaine & Jayoung RyuDivision of Hematology/Oncology, Boston Children’s Hospital, Boston, MA, USALucas Ferreira, Daniel Bauer, Basheer Becerra, Eric Che, Marlena L. Starr & Ting WuDepartment of Biomedical Informatics and Medical Education, University of Washington, Seattle, WA, USASean D. Mooney, Yile Chen & Mariam BenazouzInstitute for Genomic Health, Icahn School of Medicine at Mount Sinai, New York, NY, USAVikas PejaverDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USAVikas PejaverDepartment of Bioengineering and Therapeutic Sciences, Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USAJingjing Zhao, Nadav Ahituv, Andrew Blair, Chengyu Deng, Mai Nobuhara, Nicholas F. Page, Jasmine Sims & Aki UshikiCenter for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USASteven Gazal & Artem KimDepartment of Quantitative and Computational Biology, University of Southern California, Los Angeles, CA, USASteven GazalNorris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USASteven GazalDepartment of Genetics, Yale School of Medicine, New Haven, CT, USASteven K. ReillyDepartment of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USAShamil Sunyaev, Saori Sakaue, Richard Sherwood, Matthew J. Francoeur, Ellie N. Gibbs, Quang Vinh Phan & Soumya RaychaudhuriImaging Platform, Broad Institute of Harvard and MIT, Cambridge, MA, USAAnne E. Carpenter, Zitong Sam Chen, Beth A. Cimini, Marzieh Haghighi & Shantanu SinghDepartment of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USAJason D. Buenrostro, Rachel E. Savage, Juliana Babu, Fabiana M. Duarte, Kaili Fan & Wang XiDepartment of Human Genetics, University of California Los Angeles, Los Angeles, CA, USAChongyuan Luo & Terence LiDepartment of Biological Chemistry, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USAKathrin Plath, Jason Ernst, Justin Langerman & Yu SunCenter for Advanced Genomic Technologies, Duke University, Durham, NC, USAAlejandro Barrera, Charles A. Gersbach, Gregory E. Crawford, Nahid Iglesias, Ruhi Rai, Revathy Venukuttan, Boxun Li, Taylor Anglen, Lexi R. Bounds, Marisa C. Hamilton, Siyan Liu, Sean R. McCutcheon, Christian D. McRoberts Amador, Samuel J. Reisman, Maria A. ter Weele, Josephine C. Bodle & Helen L. StreffProgram in Bioinformatics and Integrative Biology, UMass Chan Medical School, Worcester, MA, USAJill E. Moore, Kaili Fan, Zhiping Weng, Manuel Garber, Yu Fu, Natalie Haas, Nishigandha Phalke, Shuo C. Shan, Nicole Shedd & Tianxiong YuLivestrong Cancer Institutes, Department of Oncology, and Department of Biomedical Engineering, The University of Texas at Austin, Austin, TX, USAS. Stephen Yi & Daniel OsorioInterdisciplinary Life Sciences Graduate Programs (ILSGP) and Oden Institute for Computational Engineering and Sciences (ICES), The University of Texas at Austin, Austin, TX, USAS. Stephen Yi & Daniel OsorioDepartment of Pediatrics, University of California, San Diego, CA, USAKyle J. Gaulton, Maike Sander, Kyle J. Gaulton, Gaowei Wang & Han ZhuDepartment of Medical and Population Genetics, Broad Institute, Cambridge, MA, USASaori Sakaue, Soumya Raychaudhuri & Alkes PriceDepartment of Computing and Mathematical Sciences, California Institute of Technology, Pasadena, CA, USALior PachterHoward Hughes Medical Institute, Seattle, WA, USAJay ShendureSystems Immunology, Benaroya Research Institute, Seattle, WA, USAJay Shendure, John Ray, Ingrid A. Harten & Ching-Huang HoAllen Discovery Center for Cell Lineage Tracing, Seattle, WA, USAJay ShenduremRNA Center of Excellence, Sanofi Pasteur Inc, Waltham, MA, USAVikram AgarwalCenter of immunotherapy and Immunity, Seattle Children’s Research Institute, Seattle, WA, USANathan Camp, Samantha C. Dawson & Richard G. JamesBioinformatics Division, WEHI, Parkville, Victoria, AustraliaEstelle Y. Da, Nick Moore & Alan F. RubinHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USAMoez DawoodDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USAAbbye E. McEwenDepartment of Bioengineering, Stanford University School of Engineering, Stanford, CA, USAXiangmeng Shawn Cai, Julia M. Schaepe & Maya U. ShethInstitute for Computational and Mathematical Engineering, Stanford University, Stanford, CA, USASalil DeshpandeDepartment of Pediatrics, Stanford University School of Medicine, Stanford, CA, USACasey GiffordInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USACasey GiffordDepartment of Applied Physics, Stanford University, Stanford, CA, USAWilliam J. GreenleafDivision of Pediatric Cardiology and Cardiovascular Institute, Stanford University School of Medicine, Stanford University, Stanford, CA, USASarasa Isobe, Mauro Lago-Docampo & Marlene RabinovitchAltos Labs, Redwood City, CA, USANimit JainCancer Biology Program, Stanford University School of Medicine, Stanford, CA, USASamuel H. KimImmunology Graduate Program and Department of Pathology, Stanford University School of Medicine, Stanford, CA, USAYeEun KimEuropean Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, GermanyDominik Lindenhofer & Lars M. SteinmetzDepartment of Biology, Stanford University, Stanford, CA, USAKristy S. MualimDepartment of Plant Biology, Carnegie Institution for Science, Stanford, CA, USAKristy S. MualimStanford Genome Technology Center, Palo Alto, CA, USAKevin R. Roy & Lars M. SteinmetzDepartment of Biomedical Informatics, Stanford University School of Medicine, Stanford, CA, USARiya Sinha & Riya SinhaLaboratory of Viral Interactomes, GIGA Institute, University of Liège, Liège, BelgiumGeorges Coppin & Florent LavalDonnelly Centre for Cellular and Biomolecular Research (CCBR), University of Toronto, Toronto, Ontario, CanadaAtina G. Coté, Jessica Lacoste, Chloe Reno, Frederick P. Roth, Mikko Taipale & Tanisha TeelucksinghDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, CanadaAtina G. Coté, Jessica Lacoste, Chloe Reno, Frederick P. Roth & Mikko TaipaleLunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, CanadaAtina G. Coté & Frederick P. RothTERRA Teaching and Research Centre, University of Liège, Gembloux, BelgiumFlorent LavalDepartment of Computer Science, University of Toronto, Toronto, Ontario, CanadaFrederick P. RothComputational Biology and Bioinformatics, Université Libre de Bruxelles, Brussels, BelgiumMaxime TixhonDepartment of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, USAAshley E. Dederich, Melissa K. McCoy & Bruce A. PosnerQuantitative Biomedical Research Center, Peter O’Donnell Jr School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX, USACarlos A. Pinzón-Arteaga, Lin Xu, Yanfeng Zhang & Qinbo ZhouDepartment of Pediatrics, Division of Hematology/Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USALin XuChildren’s Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USAJian XuNeuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USAHyejung Won, Jessica L. Bell, Katherine N. Degner, Won Mah, Kimberly D. Ritola, Sarah A. Schoenrock & Rachel A. SharpDepartment of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USAKimberly D. RitolaDepartment of Pediatrics, Harvard Medical School, Boston, MA, USADaniel Bauer, Basheer Becerra & Ting WuMontreal Heart Institute, Montreal, Quebec, CanadaGuillaume Lettre & Estelle LecluzeDépartement de Médecine, Université de Montréal, Montréal, Quebec, CanadaGuillaume LettreDepartment of Pathology, Massachusetts General Hospital, Boston, MA, USAEric Che, Nahye Kim, Emily M. King & Benjamin P. KleinstiverCenter for Genomic Medicine and Department of Pathology, Massachusetts General Hospital, Boston, MA, USANahye Kim, Emily M. King & Benjamin P. KleinstiverPhD Program in Biological and Biomedical Sciences, Harvard University, Boston, MA, USAEmily M. KingBroad Institute of MIT and Harvard, Boston, MA, USAZhijian Li, Zain M. Patel & Manolis KellisDepartment of Biomedical Engineering, Duke University, Durham, NC, USACharles A. Gersbach, Nahid Iglesias, Boxun Li, Lexi R. Bounds, Sean R. McCutcheon, Maria A. ter Weele, Josephine C. Bodle & Helen L. StreffDepartment of Pediatrics, Duke University, Durham, NC, USAGregory E. CrawfordDepartment of Cell Biology, Duke University Medical Center, Durham, NC, USATaylor Anglen & Samuel J. ReismanDepartment of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, USAChristian D. McRoberts AmadorDepartment of Pathology, Stanford University, Stanford, CA, USAAnsuman T. Satpathy, Jacob C. Gutierrez, Maya Kasowski, Caleb A. Lareau, Vincent Liu, Christopher S. McGinnis, Katalin Sandor, Yajie Yin, Wenxi Zhang, Andrew R. Marderstein, Stephen B. Montgomery, Evin M. Padhi & Kameron B. RodriguesParker Institute for Cancer Immunotherapy, San Francisco, CA, USAAnsuman T. Satpathy, Caleb A. Lareau, Christopher S. McGinnis, Katalin Sandor & Chun J. YeGladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USAAnsuman T. Satpathy, Jacob C. Gutierrez, Caleb A. Lareau, Vincent Liu, Christopher S. McGinnis, Katalin Sandor & Yajie YinGladstone Institute of Neurological Disease, San Francisco, CA, USAM. Ryan Corces, Serena H. Chang, Iris M. Chin, Zachary A. Gardell, Alia W. Johnson, Lucas Kampman, Shreya Menon & Adam W. TurnerDepartment of Neurology, University of California San Francisco, San Francisco, CA, USAM. Ryan Corces, Serena H. Chang, Iris M. Chin, Zachary A. Gardell, Alia W. Johnson, Lucas Kampman, Shreya Menon & Adam W. TurnerGladstone Institute of Data Science and Biotechnology, Gladstone Institutes, San Francisco, CA, USAM. Ryan Corces, Serena H. Chang, Iris M. Chin, Zachary A. Gardell, Alia W. Johnson, Lucas Kampman, Shreya Menon & Adam W. TurnerDepartment of Surgery, University of California San Francisco, San Francisco, CA, USAJames M. Gardner & Anita QuallsDiabetes Center, University of California San Francisco, San Francisco, CA, USAJames M. Gardner & Anita QuallsSean N Parker Center for Allergy and Asthma Research, Stanford University, Stanford, CA, USAMaya KasowskiBerlin Institute of Health at Charité—Universitätsmedizin Berlin, Berlin, GermanyLeif S. LudwigMax-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Institute for Medical Systems Biology (BIMSB), Berlin, GermanyLeif S. LudwigInstitute for Human Genetics, Department of Medicine, Division of Rheumatology, University of California, San Francisco, CA, USAChun J. YeChan Zuckerberg Biohub, San Francisco, CA, USAChun J. Ye & Katherine S. PollardRichard N. Merkin Institute for Translational Research, California Institute of Technology, Pasadena, CA, USABarbara J. WoldDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, USAMaria Carilli & Nikki SwarnaDepartment of Neurobiology and Behavior, UC Irvine, Irvine, CA, USAKim GreenDepartment of Pharmaceutical Sciences, UC Irvine, Irvine, CA, USAJasmine SakrDepartment of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI, USAAndre Guerra & Maureen A. SartorDepartment of Statistical Science, Duke University, Durham, NC, USASayan MukherjeeDepartment of Mathematics, Duke University, Durham, NC, USASayan MukherjeeDepartment of Computer Science, Duke University, Durham, NC, USASayan Mukherjee & Raluca GordanDepartment of Biology, Duke University, Durham, NC, USAYuncheng DuanDepartment of Genetics, Harvard Medical School, Boston, MA, USAArun DurvasulaMIT Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USAManolis KellisDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USALilia M. Iakoucheva & Tulika KakatiDepartment of Genetics, University of Wisconsin, Madison, WI, USAAudrey Gasch & Eduardo ScopelDepartment of Statistics, University of Wisconsin, Madison, WI, USAKunling HuangDepartment of Computer Sciences, University of Wisconsin, Madison, WI, USAMichael OhtakeDepartment of Pediatrics, University of Wisconsin, Madison, WI, USARobert D. SteinerPreventionGenetics Inc., Part of Exact Sciences, Marshfield, WI, USARobert D. SteinerMarshfield Clinic Health System, Marshfield, WI, USARobert D. SteinerDepartment of Data Science, Dana-Farber Cancer Institute, Boston, MA, USAYi ZhangDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USAAlexis BattleMalone Center for Engineering in Healthcare, Johns Hopkins University, Baltimore, MD, USAAlexis BattleDepartment of Computer Science, Johns Hopkins University, Baltimore, MD, USAAlexis BattleDepartment of Genetic Medicine, Johns Hopkins University, Baltimore, MD, USAAlexis BattleDepartment of Biomedical Data Science, Stanford University, Stanford, CA, USAStephen B. MontgomeryCenter for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, OH, USADaniel McGrailDepartment of Genetics, University of Pennsylvania, Philadelphia, PA, USAHao Wu, Ziyue Gao, Julia I. Leu, Fan Li, Dongming Liang, Qi Qiu, Sarah Tishkoff, Ning Xie & Hongjie ZhangDepartment of Electrical and Computer Engineering, University of Washington, Seattle, WA, USASreeram KannanDepartment of Neuroscience, University of Pennsylvania, Philadelphia, PA, USAHongjun Song, Ronni Kurzion, Guo-li Ming, Yijing Su, Qian Yang & Zhijian ZhangDepartment of Medicine, University of Pennsylvania, Philadelphia, PA, USAJingli Cai, Kiran Musunuru & Wenli YangDepartment of Cancer Biology, University of Pennsylvania, Philadelphia, PA, USAJunwei ShiDepartment of Biomedical Engineering and McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University, Baltimore, MD, USAMichael A. Beer, Jin Woo Oh, Milad Razavi-Mohseni, Dustin Shigaki & Yunxiao YangDepartment of Biochemistry, Albert Einstein College of Medicine, Bronx, NY, USARonald Cutler & Simone SidoliWeill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, New York, NY, USARachel A. GlennDepartment of Cellular and Molecular Medicine, University of California, San Diego, CA, USABing Ren, Weronika Bartosik, Hannah S. Indralingam, Nathan R. Zemke & Kai ZhangCenter for Epigenomics, University of California, San Diego, CA, USABing RenBioinformatics and Systems Biology Program, University of California, San Diego, CA, USAAdam Klie & Hannah MummeyBiomedical Sciences Program, University of California, San Diego, CA, USAMei-Lin OkinoDepartment of Neurology, University of California Los Angeles, Los Angeles, CA, USANoah ZaitlenHoward Hughes Medical Institute and Immunology Program at Sloan Kettering Institute, New York, NY, USAAlexander Y. RudenskyLudwig Center for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY, USAAlexander Y. RudenskyDivision of Rheumatology, Department of Medicine, Hospital for Special Surgery, New York, NY, USAMelanie H. Smith, Laura T. Donlin & Amit LakhanpalWeill Cornell Medical College and Graduate School, New York, NY, USALaura T. DonlinProgram in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USAMark B. Gerstein, Beatrice Borsari & Joel RozowskyDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USAMark B. Gerstein, Beatrice Borsari & Joel RozowskyDepartment of Computer Science, Yale University, New Haven, CT, USAMark B. GersteinDepartment of Statistics and Data Science, Yale University, New Haven, CT, USAMark B. GersteinDepartment of Biomedical Informatics and Data Science, Yale University, New Haven, CT, USAMark B. GersteinCenter for Genetic Medicine and Department of Cell and Developmental Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USARex L. ChisholmDepartment of Pediatrics, Washington University, St Louis, MO, USAPatricia DicksonDepartment of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Evanston, IL, USAYuan LuoUC Santa Cruz Genomics Institute, University of California Santa Cruz, Santa Cruz, CA, USAKaren H. MigaDepartment of Medicine, Washington University, St Louis, MO, USANathan StitzielCenter for Genetic Medicine, Department of Pharmacology, Northwestern University, Chicago, IL, USABarbara E. StrangerDepartment of Developmental Biology, Washington University, St Louis, MO, USABo ZhangDepartment of Pathology and Immunology, Washington University, St Louis, MO, USAGuoyan ZhaoDepartment of Neurology, Washington University, St Louis, MO, USAGuoyan ZhaoDepartments of Psychiatry and Genetics, Division of Molecular Psychiatry, Department of Genetics, Wu Tsai Institute, Yale University School of Medicine, New Haven, CT, USAKristen BrennandDepartment of Genetics and Development, Institute for Cancer Genetics, Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY, USAAlberto Ciccia, Samuel B. Hayward, Jen-Wei Huang, Giuseppe Leuzzi, Angelo Taglialatela, Tanay Thakar & Alina VaitsiankovaCincinnati Children’s Hospital, Cincinnati, OH, USAH. Leighton Grimes & Nathan SalomonisInstitute of Computational Biology, Helmholtz Zentrum Munich, Neuherberg, GermanyMatthias Heinig & Corinna LosertDepartment of Computer Science, School of Computation, Information and Technology, Technical University Munich, Munich, GermanyMatthias Heinig & Corinna LosertMunich Heart Alliance, DZHK (German Center for Cardiovascular Research), Munich, GermanyMatthias HeinigPaul G. Allen School of Computer Science and Engineering, University of Washington, Seattle, WA, USASara Mostafavi, Alexander Sasse & Anna SpiroCanadian Institute for Advanced Research, Toronto, Ontario, CanadaSara MostafaviLawrence Berkeley National Laboratory, Berkeley, CA, USALen A. Pennacchio, Momoe Kato, Michael Kosicki, Brandon Mannion, Neil Slaven & Axel ViselDOE Joint Genome Institute, Berkeley, CA, USALen A. Pennacchio & Axel ViselGladstone Institutes, San Francisco, CA, USAKatherine S. Pollard, Shiron Drusinsky & Sean WhalenUniversity of California, San Francisco, CA, USAKatherine S. Pollard & Shiron DrusinskyDepartment of Immunology, University of Washington, Seattle, WA, USAJohn RayNew York Genome Center, New York, NY, USANeville E. Sanjana, Christina Caragine & John A. MorrisDepartment of Biology, New York University, New York, NY, USANeville E. Sanjana, Christina Caragine & John A. MorrisSt Anna Children’s Cancer Research Institute (CCRI), Vienna, AustriaDavide Seruggia, Ana Patricia Kutschat & Sandra WittibschlagerCeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, AustriaDavide Seruggia, Ana Patricia Kutschat & Sandra WittibschlagerDivision of Genomic Medicine, National Human Genome Research Institute (NHGRI), National Institutes of Health (NIH), Bethesda, MD, USAZo BlyDepartment of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, NY, USAStephanie CalluoriMasters of Physician Assistant Studies Program, Colorado Mesa University, Grand Junction, CO, USAElla K. SamerJ.M.E., H.A.L. and H. Singh co-led the Writing Group. J.M.E., H.A.L., H. Singh, L. M. Starita, G.C.H., H. Carter, N. Sahni, T.E.R., X. Lin, Y. Li, N.V.M., M.H.C., B.C.H. and A.M. wrote initial text based on input from principal investigators, the Writing Group, and Working Group and Focus Group co-chairs. J.M.E., A.P.B. and J. Ryu developed figures. All authors contributed to developing the vision and goals of the IGVF Consortium, outlining the project, and editing the manuscript. The role of the NHGRI Program Management in the preparation of this paper was limited to coordination and scientific management of the IGVF Consortium.
