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RNA architecture of porcine deltacoronavirus genome inside virions detected by vRIC-seq

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Cell culture and virions sample preparationLilly Laboratories cell porcine kidney 1 (LLC-PK1, ATCC CL-101) cells were cultured in Minimun Essential Medium (MEM; Invitrogen) supplemented...
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A mathematical model simulating the adaptive immune response in various vaccines and vaccination strategies

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Kinetic modeling of antibody response following inactivated vaccine administrationInactivated vaccines represent a conventional approach in vaccine production. The term “inactivated vaccines” encompasses both the...
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ML-enhanced peroxisome capacity enables compartmentalization of multienzyme pathway

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Heinig, U., Gutensohn, M., Dudareva, N. & Aharoni, A. The challenges of cellular compartmentalization in plant metabolic engineering. Curr. Opin. Biotechnol. 24, 239–246 (2013).Article  ...
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A machine learning model reveals expansive downregulation of ligand-receptor interactions that enhance lymphocyte infiltration in melanoma with developed resistance to immune checkpoint blockade

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Bulk RNA-seq datasetsWe collected five publicly available bulk RNA-seq datasets from formalin-fixed-paraffin-embedded (FFPE) and fresh-frozen tumor tissue biopsies, accompanied by clinical information of melanoma...
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Expression analysis of the apple HSP70 gene family in abiotic stress and phytohormones and expression validation of candidate MdHSP70 genes

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