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Virtual resection evaluation based on sEEG propagation network for drug-resistant epilepsy

PatientsWe used two datasets: (1) Clinical data with 6 patients with 12 seizures from the neurosurgery department of Shanxi Provincial People’s Hospital; (2) HUP data with 10...

Predicting transcriptional responses to novel chemical perturbations using deep generative model for drug discovery

PRnet: perturbation-conditioned deep generative model for transcriptional response predictionIn this paper, we formulate the transcriptional response prediction as a distribution generation problem conditioned on perturbations. Cells inherently...

Differential amino acid usage leads to ubiquitous edge effect in proteomes across domains of life that can be explained by amino acid secondary structure...

Proteomes differ among distant domains of lifeTwo competing hypotheses suggest that amino acid usage in proteomes differ or not among distant groups of living organisms. The lineage-specific...

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Lemurs use long-term memory, smell, and social cues to find food

How do foraging animals find their food? A new study by New York University researchers shows that lemurs use smell, social cues, and long-term...

Multimodal tactile sensing fused with vision for dexterous robotic housekeeping

With robotics becoming increasingly entering our daily lives for assisting old people and disabled...

When is too much knowledge a bad thing?

A new study finds an increase in knowledge could be a bad thing when people use it to act in their own self-interest rather...

De novo generation of SARS-CoV-2 antibody CDRH3 with a pre-trained generative large language model

The framework of PALM-H3 and A2BinderThe workflow and model framework of the PALM-H3 and A2binder are shown in Fig. 1. The purpose of PALM-H3 is...

First noninvasive method to continually measure true blood pressure

Solving a decades-old problem, a multidisciplinary team of Caltech researchers has figured out a method to noninvasively and continually measure blood pressure anywhere on...

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