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Uncovering genetic loci and biological pathways associated with age-related cataracts through GWAS meta-analysis

CohortsTo identify risk loci for cataracts, we conducted a GWAS meta-analysis that encompasses 67,844 cases and 517,399 controls from a meta-analysis of the United Kingdom Biobank (UKB)...

Microbiome-based correction for random errors in nutrient profiles derived from self-reported dietary assessments

Overview of METRICWe aim to infer the true nutrient profile based on the assessed one and the measured gut microbial composition. A naive way to do this...

An enhanced deep learning method for the quantification of epicardial adipose tissue

Study populationIn this study, 108 patients aged between 48 and 70 years (mean age ± standard deviation: 60.1 years ± 6.0; 62 of 108 were men) undergoing routine CCTA scans...

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Exploring geometric deep learning and computational geometry research for manufacturing automation

While geometric deep learning and computational geometry are making strides in fields like drug...

Divergent recruitment of developmentally defined neuronal ensembles supports memory dynamics | Science

Memories are dynamic constructs whose properties change with time and experience. The biological mechanisms underpinning these dynamics remain elusive, particularly concerning how shifts in...

Hebbian instruction of axonal connectivity by endogenous correlated spontaneous activity | Science

Spontaneous activity refines neural connectivity prior to the onset of sensory experience, but it remains unclear how such activity instructs axonal connectivity with subcellular...

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