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Deep learning prediction of ribosome profiling with Translatomer reveals translational regulation and interprets disease variants

Liu, Y., Beyer, A. & Aebersold, R. On the dependency of cellular protein levels on mRNA abundance. Cell 165, 535–550 (2016).Article  ...

SpliceTransformer predicts tissue-specific splicing linked to human diseases

Data representationThe input for the model is pre-mRNA sequences. The nucleotides A, C, G, and T are one-hot encoded, represented as , , , and , respectively....

Cinchona plant alkaloid catalyst subtracts hydrogen to invert alcohols’ chirality | Research

Hydrogen atoms can be selectively extracted from symmetrical molecules using a catalyst readily derived from Cinchona alkaloids, researchers in the UK have shown. The researchers went on...

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Researchers help to control cancer-causing poison in corn

Corn, a staple food crop consumed by billions of people and animals worldwide, is frequently contaminated by the fungal toxin aflatoxin B1, a highly...

U.S. capable of achieving seafood independence

From lobster to haddock and seaweed, seafood plays an important role in the U.S. economy, diet and culture. The nation is one of the...

Structure and repair of replication-coupled DNA breaks | Science

Using CRISPR-Cas9 nicking enzymes, we examined the interaction between the replication machinery and single-strand breaks, one of the most common forms of endogenous DNA...

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