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Differential amino acid usage leads to ubiquitous edge effect in proteomes across domains of life that can be explained by amino acid secondary structure...

Proteomes differ among distant domains of lifeTwo competing hypotheses suggest that amino acid usage in proteomes differ or not among distant groups of living organisms. The lineage-specific...

Virtual resection evaluation based on sEEG propagation network for drug-resistant epilepsy

PatientsWe used two datasets: (1) Clinical data with 6 patients with 12 seizures from the neurosurgery department of Shanxi Provincial People’s Hospital; (2) HUP data with 10...

Predicting transcriptional responses to novel chemical perturbations using deep generative model for drug discovery

PRnet: perturbation-conditioned deep generative model for transcriptional response predictionIn this paper, we formulate the transcriptional response prediction as a distribution generation problem conditioned on perturbations. Cells inherently...

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‘Banana apocalypse’ could be averted thanks to genetic breakthrough

Researchers have made a breakthrough in the race to save the world's bananas from a devastating disease that could wipe them out, according to...

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In recent years, public health measures, surveillance, and vaccination have helped bring about significant progress in reducing the impact of seasonal flu epidemics, caused...

‘Spectacular silver treasure’ from Viking Age unearthed by college student on farm in Denmark

A college student in Denmark has unearthed a "spectacular silver treasure" of Viking Age jewelry that doubled as money.Gustav Bruunsgaard, a metal detectorist and...

Forest loss intensifies climate change by increasing temperatures and cloud level, which leads to decrease of water

Montane forests are often cloudy, wet, cold, and occur on isolated mountains in Africa. They are rich in biodiversity and act as water towers...

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