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Differential amino acid usage leads to ubiquitous edge effect in proteomes across domains of life that can be explained by amino acid secondary structure...

Proteomes differ among distant domains of lifeTwo competing hypotheses suggest that amino acid usage in proteomes differ or not among distant groups of living organisms. The lineage-specific...

Virtual resection evaluation based on sEEG propagation network for drug-resistant epilepsy

PatientsWe used two datasets: (1) Clinical data with 6 patients with 12 seizures from the neurosurgery department of Shanxi Provincial People’s Hospital; (2) HUP data with 10...

Identification of diagnostic markers pyrodeath-related genes in non-alcoholic fatty liver disease based on machine learning and experiment validation

Cusi, K. et al. Non-alcoholic fatty liver disease (NAFLD) prevalence and its metabolic associations in patients with type 1 diabetes and type 2 diabetes. Diabetes Obes. Metab....

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For some older adults with kidney failure, dialysis may not be the best option

Whether dialysis is the best option for kidney failure and, if so, when to start, may deserve more careful consideration, according to a new...

Less severe forest fires can reduce intensity of future blazes

Not all forest fires have devastating effects. Low- and moderate-severity forest wildfires can reduce the intensity of future conflagrations for as long as 20...

‘Final parsec problem’ that makes supermassive black holes impossible to explain could finally have a solution

Scientists have been modeling how supermassive black holes form when two smaller black holes merge. But in their simulations, most pairs of massive black...

Peering into the mind of artificial intelligence to make better antibiotics

Artificial intelligence (AI) has exploded in popularity. It powers models that help us drive vehicles, proofread emails and even design new molecules for medications....

Weather patterns as a major contributing factor to complex air pollution

"Complex pollution" usually refers to the environmental pollution phenomenon formed by the simultaneous presence of multiple pollutants in the same environment. In China, the...

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