A High-Resolution Structural Characterization and Physicochemical Study of How a Peptoid Binds to an Oncoprotein MDM2

Chem. Sci., 2024, Accepted ManuscriptDOI: 10.1039/D4SC01540A, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Marin Yokomine, Jumpei Morimoto, Yasuhiro Fukuda, Takumi Ueda, Koh Takeuchi, Koji Umezawa, Hideo Ago, Hiroaki Matsuura, Go Ueno, Akinobu Senoo, Satoru Nagatoishi, Kouhei Tsumoto, Shinsuke SandoPeptoids are a promising drug modality targeting disease-related proteins, but how a peptoid engages in protein binding is poorly understood. This is primarily due to a lack of high-resolution peptoid–protein…The content of this RSS Feed (c) The Royal Society of Chemistry

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