The relationship between cardiovagal baroreflex and cerebral autoregulation in postural orthostatic tachycardia disorder using advanced cross-correlation function

Schondorf, R. & Low, P. A. Idiopathic postural orthostatic tachycardia syndrome: an attenuated form of acute pandysautonomia? Neurology. 43 (1_part_1), 132–132 (1993).Article 
CAS 
PubMed 

Google Scholar 
Satish, R. et al. Canadian Cardiovascular Society Position Statement on Postural Orthostatic Tachycardia Syndrome (POTS) and related disorders of Chronic Orthostatic Intolerance. Can. J. Cardiol. 36 (3), 357–372 (2020).Article 

Google Scholar 
Vernino, S. et al. Postural orthostatic tachycardia syndrome (POTS): state of the science and clinical care from a 2019 National institutes of Health Expert Consensus Meeting – Part 1. Auton. Neurosci. 235, 102828 (2021).Article 
PubMed 
PubMed Central 

Google Scholar 
Blitshteyn, S. Is postural orthostatic tachycardia syndrome (POTS) a central nervous system disorder? J. Neurol. 269 (2), 725–732 (2022).Article 
PubMed 

Google Scholar 
Mar, P. L. & Raj, S. R. Postural Orthostatic Tachycardia Syndrome: mechanisms and New therapies. Annu. Rev. Med. 71, 235–248 (2020).Article 
CAS 
PubMed 

Google Scholar 
Nardone, M., Guzman, J., Harvey, P. J., Floras, J. S. & Edgell, H. Effect of a neck compression collar on cardiorespiratory and cerebrovascular function in postural orthostatic tachycardia syndrome (POTS). J. Appl. Physiol. 128 (4), 907–913 (2020).Article 
CAS 
PubMed 

Google Scholar 
Swai, J. et al. Heart rate and heart rate variability comparison between postural orthostatic tachycardia syndrome versus healthy participants; a systematic review and meta-analysis. BMC Cardiovasc. Disord. 19, 320 (2019).Article 
PubMed 
PubMed Central 

Google Scholar 
Stewart, J. M., Warsy, I. A., Visintainer, P., Terilli, C. & Medow, M. S. Supine Parasympathetic Withdrawal and Upright Sympathetic Activation Underly abnormalities of the Baroreflex in Postural Tachycardia Syndrome: effects of Pyridostigmine and Digoxin. Hypertension. 77 (4), 1234–1244 (2021).Article 
CAS 
PubMed 

Google Scholar 
Boris, J. R. Postural orthostatic tachycardia syndrome in children and adolescents. Auton. Neurosci. 215, 97–101 (2018).Article 
PubMed 

Google Scholar 
Novak, P., Felsenstein, D., Mao, C., Octavien, N. R. & Zubcevik, N. Association of small fiber neuropathy and post treatment Lyme disease syndrome. PLoS One. 14 (2), e0212222 (2019).Article 
CAS 
PubMed 
PubMed Central 

Google Scholar 
Grubb, A. F. & Grubb, B. P. Postural orthostatic tachycardia syndrome: new concepts in pathophysiology and management. Trends Cardiovasc. Med. S1050-1738 (21), 00122–00125 (2021).
Google Scholar 
Olshansky, B. et al. Postural Orthostatic Tachycardia Syndrome (POTS): a critical assessment. Prog. Cardiovasc. Dis. 63 (3), 263–270 (2020).Article 
PubMed 
PubMed Central 

Google Scholar 
Bourne, K. M. et al. Postural orthostatic tachycardia syndrome is associated with significant employment and economic loss. J. Intern. Med. 290 (1), 203–212 (2021).Article 
PubMed 
PubMed Central 

Google Scholar 
Swai, J., Hu, Z., Zhao, X., Rugambwa, T. & Ming, G. Heart rate and heart rate variability comparison between postural orthostatic tachycardia syndrome versus healthy participants; a systematic review and meta-analysis. BMC Cardiovasc. Disord. 19 (1), 320 (2019).Article 
PubMed 
PubMed Central 

Google Scholar 
Mallien, J., Isenmann, S., Mrazek, A. & Haensch, C. A. Sleep disturbances and autonomic dysfunction in patients with postural orthostatic tachycardia syndrome. Front. Neurol. 5, 118 (2014).Article 
PubMed 
PubMed Central 

Google Scholar 
Julia, B. & Reiner, B. The postural orthostatic stress syndrome in childhood: HRV analysis and the active standing test. Prev. Med. 3, 1–7 (2020).
Google Scholar 
Carew, S. et al. A review of postural orthostatic tachycardia syndrome. Europace: Eur. Pacing Arrhythm. Cardiac Electrophysiol. : J. Working Groups Cardiac Pacing Arrhythm. Cardiac Cell. Electrophysiol. Eur. Soc. Cardiol. 11 (1), 18–25 (2009).
Google Scholar 
van der Zalm, T. et al. Postural orthostatic tachycardia syndrome (POTS): a common but unfamiliar syndrome. Neth. J. Med. 77 (1), 3–9 (2019).PubMed 

Google Scholar 
Williams, E. L. et al. Salt supplementation in the management of orthostatic intolerance: Vasovagal syncope and postural orthostatic tachycardia syndrome. Auton. Neurosci. Basic Clin. 237, 102906 (2022).Blitshteyn, S. & Whitelaw, S. Postural orthostatic tachycardia syndrome (POTS) and other autonomic disorders after COVID-19 infection: a case series of 20 patients. Immunol. Res. 69 (2), 205–211 (2021).Article 
CAS 
PubMed 
PubMed Central 

Google Scholar 
Miglis, M. G. et al. A case report of postural tachycardia syndrome after COVID-19. Clin. Auton. Research: Official J. Clin. Auton. Res. Soc. 30 (5), 449–451 (2020).Article 

Google Scholar 
Oketa-Onyut Julu, P. Normal autonomic neurophysiology of postural orthostatic tachycardia and recommended physiological assessments in postural orthostatic tachycardia syndrome. Physiol. Rep. 8 (12), e14465 (2020).Article 
CAS 
PubMed 
PubMed Central 

Google Scholar 
Laitinen, T. et al. Age and gender dependency of baroreflex sensitivity in healthy subjects. J. Appl. Physiol. (1985). 84 (2), 576–583 (1998).Article 
CAS 
PubMed 

Google Scholar 
Lanfranchi, P. A. & Somers, V. K. Arterial baroreflex function and cardiovascular variability: interactions and implications. Am. J. Physiol. Regul. Integr. Comp. Physiol. 283 (4), R815–R826 (2002).Article 
PubMed 

Google Scholar 
Jíra, M., Závodná, E., Honzíková, N., Nováková, Z. & Fiser, B. Baroreflex sensitivity is an individual characteristic feature. Physiol. Res. 55 (3), 349–351 (2006).Article 
PubMed 

Google Scholar 
La Rovere, M. T., Pinna, G. D. & Raczak, G. Baroreflex sensitivity: measurement and clinical implications. Annals Noninvasive Electrocardiology: Official J. Int. Soc. Holter Noninvasive Electrocardiol. Inc. 13 (2), 191–207 (2008).Article 

Google Scholar 
Dutra-Marques, A. C. et al. She exaggerated exercise blood pressure as a marker of baroreflex dysfunction in normotensive metabolic syndrome patients. Front. NeuroSci. 15, 680195 (2021).Article 
PubMed 
PubMed Central 

Google Scholar 
Michal Javorka, Z. et al. Baroreflex analysis in diabetes mellitus: linear and nonlinear approaches. Med. Biol. Eng. Comput. 49, 279–288 (2011).Xiao, M. X. et al. Application of a speedy modified entropy method in assessing the complexity of baroreflex sensitivity for age-controlled healthy and diabetic subjects. Entropy 21(9), 894 (2019).Cseh, D. et al. Type 2 Diabetes Mellitus Is Independently Associated With Decreased Neural Baroreflex Sensitivity: The Paris Prospective Study III. Thromb. Vascular Biology, 40(5), 1420–1428. (2020).Article 
CAS 

Google Scholar 
Ziegler, D. et al. Association of Lower Cardiovagal Tone and Baroreflex Sensitivity with Higher Liver Fat Content early in type 2 diabetes. J. Clin. Endocrinol. Metab. 103 (3), 1130–1138 (2018).Article 
PubMed 

Google Scholar 
Persson, P. B. et al. Time versus frequency domain techniques for assessing baroreflex sensitivity. J. Hypertens. 19 (10), 1699–1705 (2001).Article 
CAS 
PubMed 

Google Scholar 
Swenne, C. A. Baroreflex sensitivity: mechanisms and measurement. Neth. Heart Journal: Monthly J. Neth. Soc. Cardiol. Neth. Heart Foundation. 21 (2), 58–60 (2013).Article 
CAS 

Google Scholar 
Kawada, T., Saku, K. & Miyamoto, T. Closed-Loop Identification of Baroreflex Properties in the frequency domain. Front. NeuroSci. 15, 694512 (2021).Article 
PubMed 
PubMed Central 

Google Scholar 
Laude, D. et al. Comparison of various techniques to estimate spontaneous baroreflex sensitivity (the EuroBaVar study). Am. J. Physiol. Regul. Integr. Comp. Physiol. 286 (1), R226–R231 (2004).Article 
CAS 
PubMed 

Google Scholar 
Medow, M. S., Del Pozzi, A. T., Messer, Z. R., Terilli, C. & Stewart, J. M. Altered oscillatory cerebral blood flow velocity and autoregulation in postural tachycardia syndrome. Front. Physiol. 5, 234 (2014).Article 
PubMed 
PubMed Central 

Google Scholar 
Schondorf, R., Benoit, J. & Stein, R. Cerebral autoregulation is preserved in postural tachycardia syndrome. J. Appl. Physiol. (1985). 99 (3), 828–835 (2005).Article 
PubMed 

Google Scholar 
Ocon, A. J., Medow, M. S., Taneja, I., Clarke, D. & Stewart, J. M. Decreased upright cerebral blood flow and cerebral autoregulation in normocapnic postural tachycardia syndrome. Am. J. Physiol. Heart Circ. Physiol. 297 (2), H664–H673 (2009).Article 
CAS 
PubMed 
PubMed Central 

Google Scholar 
Schondorf, R., Benoit, J. & Stein, R. Cerebral autoregulation in orthostatic intolerance. Ann. N Y Acad. Sci. 940, 514–526 (2001).Article 
ADS 
CAS 
PubMed 

Google Scholar 
Derrick, T. R. & Thomas, J. M. Time Series Analysis: The Cross-Correlation Function 46 (Kinesiology, 2004).
Google Scholar 
Westerhof, B. E., Gisolf, J., Stok, W. J., Wesseling, K. H. & Karemaker, J. M. Time-domain cross-correlation baroreflex sensitivity: performance on the EUROBAVAR data set. J. Hypertens. 22 (7), 1371–1380 (2004).Article 
CAS 
PubMed 

Google Scholar 
Silvani, A., Magosso, E., Bastianini, S., Lenzi, P. & Ursino, M. Mathematical modeling of cardiovascular coupling: Central autonomic commands and baroreflex control. Auton. Neuroscience: Basic. Clin. 162 (1-2), 66–71 (2011).Article 

Google Scholar 
Yeh, S. J., Lung, C. W., Jan, Y. K. & Liau, B. Y. Advanced cross-correlation function application to identify arterial Baroreflex sensitivity variations from healthy to diabetes Mellitus Front. Neurosci. 16, 812302 (2022).
Google Scholar 
Liau, B. Y. et al. Using cross-correlation analysis of multi-channel near infrared spectroscopy to assess the hemodynamic response to cupping therapy. Biomed Opt. Exp. 14(9), 4455–4467 (2023).Panerai, R. B., Kelsall, A. W., Rennie, J. M. & Evans, D. H. Analysis of cerebral blood flow autoregulation in neonates. IEEE Trans. Bio Med. Eng. 43 (8), 779–788 (1996).Article 
CAS 

Google Scholar 
Steinmeier, R. et al. Slow rhythmic oscillations of blood pressure, intracranial pressure, microcirculation, and cerebral oxygenation. The dynamic interrelation and time course in humans. Stroke. 27 (12), 2236–2243 (1996).Article 
CAS 
PubMed 

Google Scholar 
Czosnyka, M., Smielewski, P., Kirkpatrick, P., Menon, D. K. & Pickard, J. D. Monitoring of cerebral autoregulation in head-injured patients. Stroke. 27 (10), 1829–1834 (1996).Article 
CAS 
PubMed 

Google Scholar 
Chiu, C. C. & Yeh, S. J. Assessment of cerebral autoregulation using time-domain cross-correlation analysis. Comput. Biol. Med. 31 (6), 471–480 (2001).Article 
CAS 
PubMed 

Google Scholar 
Panerai, R. B. et al. Multivariate dynamic analysis of cerebral blood flow regulation in humans. IEEE Trans. Bio Med. Eng. 47 (3), 419–423 (2000).Article 
CAS 

Google Scholar 
Chiu, C. C., Yeh, S. J. & Liau, B. Y. Assessment of Cerebral Autoregulation dynamics in diabetics using Time-Domain Cross-correlation Analysis. J. Med. Bio Eng. 25 (2), 53–59 (2005).
Google Scholar 
Nasr, N. et al. Baroreflex and cerebral autoregulation are inversely correlated. Circ. J. 78 (10), 2460–2467 (2014).Article 
PubMed 

Google Scholar 
Novak, P. & Marciano, S. Hypocapnic Orthostatic Intolerance with (POTS) and without (HYCH) tachycardia represent a spectrum of the same disorder (S43. 003). Neurology. 100 (17_supplement_2), 3757 (2023).Article 

Google Scholar 
Saha, L. Irritable bowel syndrome: pathogenesis, diagnosis, treatment, and evidence-based medicine. World J. Gastroenterol. 20 (22), 6759–6773 (2014).Article 
PubMed 
PubMed Central 

Google Scholar 
Camilleri, M. Diagnosis and treatment of irritable bowel syndrome: a review. Jama. 325 (9), 865–877 (2021).Article 
CAS 
PubMed 

Google Scholar 

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