Catalytic prenyl conjugate additions for synthesis of enantiomerically enriched PPAPs | Science


Polycyclic polyprenylated acylphloroglucinols (PPAPs) are a class of >400 natural products with a broad spectrum of bioactivity, ranging from antidepressant and antimicrobial to anti-obesity and anticancer activity. Here, we present a scalable, regio-, …

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