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Polygenic risk and rare variant gene clustering enhance cancer risk stratification for breast and prostate cancers

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Disease risk can be stratified according to PRS in conjunction with monogenic variants in high-risk genes11,13,21. Using the EPRS approach, we systematically categorized monogenic...

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Integrating Kalman filter noise residue into U-Net for robust image denoising: the KU-Net model

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In the field of image processing, the U-Net architecture has grown to be indispensable, especially for tasks like segmentation, denoising, and restoration. U-Net was...

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De novo protein design with a denoising diffusion network independent of pretrained structure prediction models

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Huang, P. S., Boyken, S. E. & Baker, D. The coming of age of protein design. Nature 537, 320–327 (2016).Article CAS ...

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AutoGater: a weakly supervised neural network model to gate cells in flow cytometric analyses

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Experiments to generate flow cytometry and CFU training dataAll experiments used the S288C wild-type strain of S. cerevisiae23. In order to train the model,...

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A large multi-focus dataset for white blood cell classification

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Stouten, K., Riedl, J. A., Levin, M.-D. & Van Gelder, W. Examination of peripheral blood smears: Performance evaluation of a digital microscope system using...

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