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PEMPS: a phylogenetic software tool to model the evolution of metabolic pathways | BMC Bioinformatics

PEMPS is a Linux command line-executable Python program that can simulate the evolution of an input metabolic pathway over an input phylogeny and report...

TopoDoE: a design of experiment strategy for selection and refinement in ensembles of executable gene regulatory networks | BMC Bioinformatics

Average number of differences between GRNsTo measure the number of differences between candidate GRNs topologies, we considered GRNs as directed graphs where nodes were...

Influence of environmental, geographic, socio-demographic, and epidemiological factors on presence of malaria at the community level in two continents

World Health Organization. World malaria report 2023. WHO Geneva. Technical report at https://www.who.int/publications/i/item/9789240086173 (2023).World Health Organization. World malaria report 2019. WHO Geneva. Technical report...

Unsupervised representation learning of chromatin images identifies changes in cell state and tissue organization in DCIS

A large-scale high-resolution chromatin imaging dataset of tissue microarrays enables the analysis of disease stages and phenotypic categories in DCISCellular chromatin organization is highly...

The variation landscape of CYP2D6 in a multi-ethnic Asian population

While extensive research has been conducted on CYP2D6 across various ethnicities, a gap still exists in understanding the extent of CYP2D6 pharmacogenetic diversity within...

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