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SARS-CoV-2 variants induce increased inflammatory gene expression but reduced interferon responses and heme synthesis as compared with wild type strains

Description of study subjectsCOVID-19 patients with Asymptomatic or Symptomatic disease were recruited and their disease severity assessed based on the WHO ordinal scoring (Table 1, S Table 1)21. We...

SMARTINI3 parametrization of multi-scale membrane models via unsupervised learning methods

Force fieldIn this study, each lipid molecule is characterized by one hydrophilic head and two hydrophobic tails, representing choline and phosphate groups, and the fatty chain of...

Understanding fine root decomposition in the context of the root economics space (RES)

Saheed Olaide Jimoh (@sahjim05), University of Wyoming, discusses his article: Traits associated with the conservation gradient are the strongest predictors of early-stage fine root decomposition rates Kahikatea (Dacrycarpus...

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Millions of years for plants to recover from global warming

Scientists often seek answers to humanity's most pressing challenges in nature. When it comes to global warming, geological history offers a unique, long-term perspective....

New supercomputing network could lead to AGI, scientists hope, with 1st node coming online within weeks

Researchers plan to accelerate the development of artificial general intelligence (AGI) with a worldwide network of extremely powerful computers — starting with a new...

Non-invasive detection of hazardous materials with a thermal-to-epithermal neutron station: a feasibility study towards practical application

Bełdowski, J., Brenner, M. & Lehtonen, K. K. Contaminated by war: A brief history of sea-dumping of munitions. Mar. Environ. Res. 162, 105189. https://doi.org/10.1016/j.marenvres.2020.105189...

Amyloid transformations of phenol soluble modulin α1 in Staphylococcus aureus and their modulation deploying a prenylated chalcone

Isobavachalcone stably binds and interacts with the amyloid core of PSM α1The top docking clusters of PSM α1 bound to IBC, demonstrated the engagement...

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