Chem. Sci., 2024, 15,11572-11583DOI: 10.1039/D4SC02908A, Edge Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Laurence Maschio, Catherine R. Back, Jawaher Alnawah, James I. Bowen, Samuel T. Johns, Sbusisiwe Z. Mbatha, Li-Chen Han, Nicholas R. Lees, Katja Zorn, James E. M. Stach, Martin A. Hayes, Marc W. van der Kamp, Christopher R. Pudney, Steven G. Burston, Christine L. Willis, Paul R. RaceA molecular description of the complete reaction cycle of the bona fide natural Diels–Alderase AbyU is presented, revealing the mechanistic intricacies of this enzyme system.The content of this RSS Feed (c) The Royal Society of Chemistry