Controlling the regioselectivity of the bromolactonization reaction in HFIP

Chem. Sci., 2024, Advance ArticleDOI: 10.1039/D4SC01503G, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Tuong Anh To, Nhu T. A. Phan, Binh Khanh Mai, Thanh Vinh NguyenExperimental and computational studies revealed the crucial role of HFIP in regioselectivity-switchable bromolactonization reactions, with the formation of endo-products under kinetic control and exo-products under thermodynamic control.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry