Palladium-catalyzed asymmetric hydrogenation of lactones under base-free conditions

Chem. Sci., 2024, 15,11038-11042DOI: 10.1039/D4SC01890G, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Han Wang, Shan-Shan Xun, Chang-Bin Yu, Yong-Gui ZhouWe present a palladium-catalyzed asymmetric hydrogenation of lactones under base-free conditions through DKR and KR with high enantioselectivity. This work provides a new strategy for asymmetric hydrogenation of esters under base-free conditions.The content of this RSS Feed (c) The Royal Society of Chemistry