Synthesis of constrained bicycloalkanes through bibase-promoted brook rearrangement/radical-polar crossover cyclization

Chem. Sci., 2024, 15,11092-11098DOI: 10.1039/D4SC02532F, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Xinke Ouyang, Bingyao Shi, Yuanyuan Zhao, Zhimin Zhu, Ziyang Li, Yuxin Yang, Chao ShuA concise protocol for the synthesis of constrained bicycloalkanes has been developed, using easily obtainable α-silyl alcohols and alkenes through a bibase-promoted brook rearrangement/radical-polar crossover cyclization (RPCC) process.The content of this RSS Feed (c) The Royal Society of Chemistry