Embargoed until:
Publicly released:
2024-07-18 01:00
Women with endometriosis could also be at higher risk of ovarian cancer, according to international researchers who say the type of endometriosis also seems to affect the risk and cancer type. The team found women with endometriosis had a 4.2-fold higher ovarian cancer risk than those without endometriosis, but women with ovarian endometriomas (cysts) and/or deep infiltrating endometriosis had a 9.7-fold higher risk compared to those without. The type of cancer also seemed to change with the endometriosis subtype, with the associations being much higher for type I ovarian cancer compared to type II ovarian cancer. According to the lead author, while ovarian cancer is still a fairly rare cancer, the results show that women with endometriosis, especially the more severe subtypes, should receive targeted cancer screening and prevention strategies to catch these cancers early.
Journal/conference: JAMA
Link to research (DOI): 10.1001/jama.2024.9210
Organisation/s: University of Utah, USA
Funder: We acknowledge partial support
for the UPDB through grant P30 CA2014 from the
NCI, University of Utah, and the University of Utah’s
program in Personalized Health and Center for
Clinical and Translational Science. This research was
also supported by the National Center for Research
Resources grant, “Sharing Statewide Health Data
for Genetic Research” (R01 RR021746), with
additional support from the Utah Department of
Health and Human Services and the University of
Utah. Additionally, this research was supported by
the Utah Cancer Registry, which is funded by the
NCI’s SEER Program (contract No.
HHSN261201800016I), the US Centers for Disease
Control and Prevention’s National Program of
Cancer Registries (cooperative agreement No.
NU58DP007131), with additional support from the
University of Utah and Huntsman Cancer
Foundation. Research reported in this publication
was also supported by the National Institutes of
Health (award No. R01HL164715 [Drs Farland,
Schliep, and Pollack], K00 CA212222 [Dr Barnard],
and K01AG058781 [Dr Schliep]), by the Huntsman
Cancer Institute’s Breast and Gynecologic Cancers
Center, and by the Doris Duke Foundation’s
COVID-19 Fund to Retain Clinical Scientists funded
by the American Heart Association.
Attachments:
Note: Not all attachments are visible to the general public