Asymmetric synthesis of unnatural α-amino acids through photoredox-mediated C–O bond activation of aliphatic alcohols

Chem. Sci., 2024, Advance ArticleDOI: 10.1039/D4SC00403E, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Gregory R. Alvey, Elena V. Stepanova, Andrey Shatskiy, Josefin Lantz, Rachel Willemsen, Alix Munoz, Peter Dinér, Markus D. KärkäsA practical protocol for the stereoselective synthesis of unnatural α-amino acids is disclosed, using ubiquitous aliphatic alcohols as radical precursors to form the α-amino acid backbone under redox-neutral photoredox-mediated conditions.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry