Ecofriendly micellar mediated spectrofluorimetric method for ultrasensitive quantification of the antiparkinsonian drug safinamide in pharmaceutical formulation and spiked human plasma

Magdy, G., Belal, F. & El-Deen, A. K. Green synchronous spectrofluorimetric method for the simultaneous determination of agomelatine and venlafaxine in human plasma at part per billion levels. Sci. Rep. 12, 1–11 (2022).Article 

Google Scholar 
Attia, K. A. M. et al. Application of different spectrofluorimetric methods for determination of lesinurad and allopurinol in pharmaceutical preparation and human plasma. Spectrochim. Acta Part A Mol. Biomol. Spectrosc. 244, 1–7 (2021).Article 

Google Scholar 
Salman, B. I., et al. Approach for reduction of the consumed solvent and quantification of avapritinib in biological (2024). https://doi.org/10.1039/d4ra01198h.Wang, C. C., Silva, R. A., Masi, A. N. & Fernandez, L. Sensitive surfactant-mediated spectrofluorimetric determination of sildenafil. Anal. Methods 2, 519–524. https://doi.org/10.1039/b9ay00208a (2010).Article 
CAS 

Google Scholar 
Atia, N. N., Mahmoud, A. M., El-Shabouri, S. R. & El-Koussi, W. M. Two validated spectrofluorometric methods for determination of gemifloxacin mesylate in tablets and human plasma. Int. J. Anal. Chem. https://doi.org/10.1155/2013/137279 (2013).Article 
PubMed 
PubMed Central 

Google Scholar 
Abdulrazik, S. G., Attia, T. Z. & Derayea, S. M. The first spectrofluorimetric protocol for sensitive quantitative analysis of bromocriptine in its pure and pharmaceutical forms: Evaluation of the greenness of the method. RSC Adv. 13, 35733–35740 (2023).Article 
ADS 
CAS 
PubMed 
PubMed Central 

Google Scholar 
El-Masry, A. A., Hammouda, M. E. A., El-Wasseef, D. R. & El-Ashry, S. M. Eco-friendly green liquid chromatographic separations of a novel combination of azelastine and fluticasone in the presence of their pharmaceutical dosage form additives. Curr. Anal. Chem. 16, 277–286 (2020).Article 
CAS 

Google Scholar 
Barakat, N. T., El-Brashy, A. M. & Fathy, M. E. Two green spectrofluorimetric methods for the assay of atomoxetine hydrochloride in pure form and commercial capsules with application to content uniformity testing. R. Soc. Open Sci. 10, 230010 (2023).Article 
ADS 
CAS 
PubMed 
PubMed Central 

Google Scholar 
Ragab, G. H., Saleh, H. M., Abdulla, N. M. & Bahgat, E. A. Development of green micellar HPLC–DAD method for simultaneous determination of some sulbactam combinations used in COVID-19 regimen. BMC Chem. 17, 94 (2023).Article 
CAS 
PubMed 
PubMed Central 

Google Scholar 
Barseem, A., Ahmed, H., El-Shabrawy, Y. & Belal, F. The use of SDS micelles as additive to increase fluorescence analysis of sitagliptin and saxagliptin derivatives in their tablets and human plasma. Microchem. J. 146, 20–24 (2019).Article 
CAS 

Google Scholar 
Derayea, S. M., Badr El-Din, K. M., Ahmed, A. S., Abdelshakour, M. A. & Oraby, M. An eco-friendly one-pot spectrofluorimetric approach for the facile determination of overactive bladder drug, tolterodine: Application to dosage forms and biological fluids. Spectrochim. Acta Part A Mol. Biomol. Spectrosc. 311, 123986. https://doi.org/10.1016/j.saa.2024.123986 (2024).Article 
CAS 

Google Scholar 
Hammad, S. F., El-Khateeb, B. Z. & El-Malla, S. F. Micelle-enhanced spectrofluorimetric determination of diphenhydramine: Application to human plasma and its simultaneous determination with naproxen in pharmaceutical tablets. Luminescence 36, 733–741 (2021).Article 
CAS 
PubMed 

Google Scholar 
Mabrouk, M. M., Noureldin, H. A. M., Badr, I. H. A. & Saad, A. H. K. Simple spectrofluorimetric methods for determination of veterinary antibiotic drug (apramycin sulfate) in pharmaceutical preparations and milk samples. Spectrochim. Acta Part A Mol. Biomol. Spectrosc. 224, 117395. https://doi.org/10.1016/j.saa.2019.117395 (2020).Article 
CAS 

Google Scholar 
Hattori, N., Tsuboi, Y., Yamamoto, A., Sasagawa, Y. & Nomoto, M. Efficacy and safety of safinamide as an add-on therapy to L-DOPA for patients with Parkinson’s disease: A randomized, double-blind, placebo-controlled, phase II/III study. Parkinsonism Relat Disord. 75, 17–23. https://doi.org/10.1016/j.parkreldis.2020.04.012 (2020).Article 
PubMed 

Google Scholar 
Sanchez Alonso, P., De La Casa-Fages, B., Alonso-Cánovas, A. & Martínez-Castrillo, J. C. Switching from rasagiline to safinamide as an add-on therapy regimen in patients with levodopa: A literature review. Brain Sci. https://doi.org/10.3390/brainsci13020276 (2023).Article 
PubMed 
PubMed Central 

Google Scholar 
Huang, P., Zhang, L. Y., Tan, Y. Y. & Di Chen, S. Links between COVID-19 and Parkinson’s disease/Alzheimer’s disease: Reciprocal impacts, medical care strategies and underlying mechanisms. Transl. Neurodegener. 12, 1–25. https://doi.org/10.1186/s40035-023-00337-1 (2023).Article 

Google Scholar 
Chaná-Cuevas, P., Salles-Gándara, P., Rojas-Fernandez, A., Salinas-Rebolledo, C. & Milán-Solé, A. The potential role of SARS-COV-2 in the pathogenesis of Parkinson’s disease. Front. Neurol. 11, 1–8. https://doi.org/10.3389/fneur.2020.01044 (2020).Article 

Google Scholar 
Cattaneo, C., Jost, W. H. & Bonizzoni, E. Long-term efficacy of safinamide on symptoms severity and quality of life in fluctuating Parkinson’s disease patients. J. Parkinson’s Dis. 10, 89–97. https://doi.org/10.3233/JPD-191765 (2020).Article 

Google Scholar 
Cruz, M. P. Xadago (Safinamide) a monoamine oxidase b inhibitor for the adjunct treatment of motor symptoms in Parkinson’s disease. Pharm Ther. 42, 622–625 (2017).
Google Scholar 
Committee for Medicinal Products for Human Use (CHMP). Assessment report Xadago International non-proprietary name: Safinamide Administrative information (2014).Zou, L. et al. Identification, characterization, and quantification of impurities of safinamide mesilate: Process-related impurities and degradation products. J. AOAC Int.. 100, 1029–1037. https://doi.org/10.5740/jaoacint.16-0218 (2017).Article 
CAS 
PubMed 

Google Scholar 
Adhao, V. S., Thenge, R. R., Sharma, J. & Thakare, M. Development and validation of stability indicating RP-HPLC method for determination of safinamide Mesylate, Jordan. J. Pharm. Sci. 13, 149–159 (2020).
Google Scholar 
El-Kosasy, A. M., Hussein, L. A., Mohamed, N. M. & Salama, N. N. New and validated RP-HPLC method for quantification of safinamide mesylate in presence of its basic degradate, levodopa and ondansetron: Application to human plasma. J. Chromatogr. Sci. 58, 789–795 (2020).Article 
CAS 
PubMed 

Google Scholar 
Zhang, K. et al. A validated chiral liquid chromatographic method for the enantiomeric separation of safinamide mesilate, a new anti-Parkinson drug. J. Pharm. Biomed. Anal. 55, 220–224 (2011).Article 
CAS 
PubMed 

Google Scholar 
Redasani, V. K., Mali, B. J., Patil, A. S. & Shirkhedkar, A. A. Development and validation of RP-HPLC method for determination of safinamide mesylate in bulk and in tablet dosage form. Anal. Chem. Indian J. 13, 127–130 (2013).CAS 

Google Scholar 
El-Sayed, H. M., Abdellatef, H. E., Hendawy, H. A. M., El-Abassy, O. M. & Ibrahim, H. DoE-enhanced development and validation of eco-friendly RP-HPLC method for analysis of safinamide and its precursor impurity: QbD approach. Microchem. J. 190, 108730. https://doi.org/10.1016/j.microc.2023.108730 (2023).Article 
CAS 

Google Scholar 
Redasani, V. K., Mali, B. J. & Surana, S. J. Development and validation of HPTLC method for estimation of safinamide mesylate in bulk and in tablet dosage form. Int. Sch. Res. Not. 2012, 1–4 (2012).
Google Scholar 
Tammisetty, M. R., Challa, B. R. & Puttagunta, S. B. Application of liquid chromatography wtih tandem mass spectrometric method for quantification of safinamide in invitro samples. Int. J. Pharma Bio Sci. 10, 55–61 (2020).CAS 

Google Scholar 
El-sayed, H. M. et al. Versatile eco-friendly electrochemical sensor based on chromium-doped zinc oxide nanoparticles for determination of safinamide aided by green assessment criteria. Microchem. J. 182, 1–8 (2022).Article 

Google Scholar 
El-Sayed, H. M. et al. Safinamide detection based on Prussian blue analogue modified solid-contact potentiometric sensor. Microchem. J. 191, 108829 (2023).
Article 
CAS 

Google Scholar 
El-Sayed, H. M., El-Abassy, O. M., Abdellatef, H. E., Hendawy, H. A. M. & Ibrahim, H. Green spectrophotometric platforms for resolving overlapped spectral signals of recently approved antiparkinsonian drug (safinamide) in the presence of its synthetic precursor (4-hydroxybenzaldehyde): Applying ecological appraisal and comparative statisti. J. AOAC Int. 106, 26–33 (2023).Article 

Google Scholar 
Abdel Moneim, M. M. & Hamdy, M. M. A. Green spectrofluorimetric methods for tramadol assay with ibuprofen or chlorzoxazone: Comparison of greenness profiles. Luminescence 36, 497–505. https://doi.org/10.1002/bio.3969 (2021).Article 
CAS 
PubMed 

Google Scholar 
Gałuszka, A., Migaszewski, Z. & Namieśnik, J. The 12 principles of green analytical chemistry and the SIGNIFICANCE mnemonic of green analytical practices. TrAC Trends Anal. Chem. 50, 78–84 (2013).Article 

Google Scholar 
Kurowska-susdorf, A., Zwier, M. & Ivankovi, A. Green analytical chemistry: Social dimension and teaching. Trends Anal. Chem. 111, 185–196. https://doi.org/10.1016/j.trac.2018.10.022 (2019).Article 
CAS 

Google Scholar 
Lotfy, H. M., El-Hanboushy, S., Fayez, Y. M., Abdelkawy, M. & Marzouk, H. M. Computational intelligence spectrophotometric scenarios for screening and quantification of single-dose triple therapy banned by the World Anti-Doping Agency in some sports. Microchem. J. 196, 1–14. https://doi.org/10.1016/j.microc.2023.109581 (2024).Article 
CAS 

Google Scholar 
Wadie, M., Abdel-moety, E. M., Rezk, M. R. & Marzouk, H. M. A novel eco-friendly HPLC method with dual detection modes for versatile quantification of dutasteride and silodosin in pharmaceutical formulation, dissolution testing and spiked human plasma. Microchem. J. 197, 1–9. https://doi.org/10.1016/j.microc.2023.109753 (2023).Article 
CAS 

Google Scholar 
Nowak, P. M., Wietecha-Posłuszny, R. & Pawliszyn, J. White analytical chemistry: An approach to reconcile the principles of green analytical chemistry and functionality. TrAC Trends Anal. Chem. 138, 15. https://doi.org/10.1016/j.trac.2021.116223 (2021).Article 
CAS 

Google Scholar 
Rostom, Y., Rezk, M. R., Wadie, M., Abdel-Moety, E. M. & Marzouk, H. M. State-of-the-art mathematically induced filtration approaches for smart spectrophotometric assessment of silodosin and solifenacin mixture in their new challenging formulation: Multi-tool greenness and whiteness evaluation. Spectrochim. Acta Part A Mol. Biomol. Spectrosc. 307, 1–14. https://doi.org/10.1016/j.saa.2023.123650 (2024).Article 
CAS 

Google Scholar 
Sajid, M. & Justyna, P. Green analytical chemistry metrics: A review. Talanta https://doi.org/10.1016/j.talanta.2021.123046 (2022).Article 
PubMed 

Google Scholar 
Hammad, S. F., El-Malla, S. F. & El-Khateeb, B. Z. Enhanced fluorimetric detection of diphenylpyraline HCl using micelle and cyclodextrin mediated approach: Spectrofluorimetric and micellar liquid chromatographic application for either single or combined formulation with caffeine and paracetamol. Spectrochim. Acta Part A Mol. Biomol. Spectrosc. 291, 122317. https://doi.org/10.1016/j.saa.2023.122317 (2023).Article 
CAS 

Google Scholar 
ICH Harmonized Tripartite Guidline. Validation of Analytical Procedures: Text and Methodology Q2 (R1) (2005)Kokosa, J. M. & Przyjazny, A. Green microextraction methodologies for sample preparations. Green Anal. Chem. 3, 100023. https://doi.org/10.1016/j.greeac.2022.100023 (2022).Article 

Google Scholar 
Płotka-Wasylka, J. & Wojnowski, W. Complementary green analytical procedure index (ComplexGAPI) and software. Green Chem. 23, 8657–8665. https://doi.org/10.1039/d1gc02318g (2021).Article 
CAS 

Google Scholar 
Pena-Pereira, F., Wojnowski, W. & Tobiszewski, M. AGREE—analytical GREEnness metric approach and software. Anal. Chem. 92, 10076–10082. https://doi.org/10.1021/acs.analchem.0c01887 (2020).Article 
CAS 
PubMed 
PubMed Central 

Google Scholar 
Manousi, N., Wojnowski, W., Płotka-Wasylka, J. & Samanidou, V. Blue applicability grade index (BAGI) and software: A new tool for the evaluation of method practicality. Green Chem. https://doi.org/10.1039/d3gc02347h (2023).Article 

Google Scholar