UNEP-WCMC Megadiverse Countries. https://www.biodiversitya-z.org/content/megadiverse-countries (accessed on 13 November 2023).Malagón, O. et al. Phytochemistry and ethnopharmacology of the Ecuadorian flora. A review. Nat. Prod. Commun. 11, 297–314 (2016).PubMedÂ
Google ScholarÂ
Armijos, C., RamÃrez, J., Salinas, M., Vidari, G. & Suárez, A. I. Pharmacology and phytochemistry of Ecuadorian medicinal plants: An update and perspectives. Pharmaceuticals 14, 1145. https://doi.org/10.3390/ph14111145 (2021).ArticleÂ
CASÂ
PubMedÂ
PubMed CentralÂ
Google ScholarÂ
Chiriboga, X. et al. New anthracene derivatives from Coussarea macrophylla. J. Nat. Prod. 66, 905–909 (2003).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Gilardoni, G., Chiriboga, X., Finzi, P. V. & Vidari, G. New 3,4-secocycloartane and 3,4-secodammarane triterpenes from the Ecuadorian plant Coussarea macrophylla. Chem. Biodivers. 12, 946–954 (2015).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Vivanco, K., Montesinos, J. V., Cumbicus, N., Malagón, O. & Gilardoni, G. The essential oil from leaves of Mauria heterophylla Kunth (Anacardiaceae): Chemical and enantioselective analyses. J. Essent. Oil. Res. https://doi.org/10.1080/10412905.2023.2266430 (2023).ArticleÂ
Google ScholarÂ
Maldonado, Y. E., Malagón, O., Cumbicus, N. & Gilardoni, G. A new essential oil from the native Ecuadorian species Steiractinia sodiroi (Hieron.) S.F. Blake (Asteraceae): Chemical and enantioselective analyses. Sci. Rep. 13, 17180 (2023).ArticleÂ
ADSÂ
CASÂ
PubMedÂ
PubMed CentralÂ
Google ScholarÂ
Gilardoni, G., Montalván, M., Ortiz, M., Vinueza, D. & Montesinos, J. V. The flower essential oil of Dalea mutisii Kunth (Fabaceae) from Ecuador chemical, enantioselective, and olfactometric analyses. Plants 9, 1403. https://doi.org/10.3390/plants9101403 (2020).ArticleÂ
CASÂ
PubMedÂ
PubMed CentralÂ
Google ScholarÂ
RamÃrez, J. et al. Chemical composition, enantiomeric analysis, AEDA sensorial evaluation and antifungal activity of the essential oil from the Ecuadorian plant Lepechinia mutica Benth (Lamiaceae). Chem. Biodivers. 14, e1700292. https://doi.org/10.1002/cbdv.201700292 (2017).ArticleÂ
CASÂ
Google ScholarÂ
Malagón, O., Cartuche, P., Montaño, A., Cumbicus, N. & Gilardoni, G. A new essential oil from the leaves of the endemic Andean species Gynoxys miniphylla Cuatrec. (Asteraceae): Chemical and enantioselective analyses. Plants 11, 398. https://doi.org/10.3390/plants11030398 (2022).ArticleÂ
CASÂ
PubMedÂ
PubMed CentralÂ
Google ScholarÂ
Maldonado, Y. E., Malagón, O., Cumbicus, N. & Gilardoni, G. A new essential oil from the leaves of Gynoxys rugulosa Muschl. (Asteraceae) growing in southern Ecuador: Chemical and enantioselective analyses. Plants 12, 849. https://doi.org/10.3390/plants12040849 (2023).ArticleÂ
CASÂ
PubMedÂ
PubMed CentralÂ
Google ScholarÂ
Cumbicus, C., Malagón, O., Cumbicus, N. & Gilardoni, G. The leaf essential oil of Gynoxys buxifolia (Kunth) Cass. (Asteraceae): A good source of furanoeremophilane and bakkenolide A. Plants 12, 1323. https://doi.org/10.3390/plants12061323 (2023).ArticleÂ
CASÂ
PubMedÂ
PubMed CentralÂ
Google ScholarÂ
Gilardoni, G., Lara, L. R., Cumbicus, N. & Malagón, O. A new leaf essential oil from endemic Gynoxys laurifolia (Kunth) Cass. of southern Ecuador: Chemical and enantioselective analyses. Plants 12, 2878. https://doi.org/10.3390/plants12152878 (2023).ArticleÂ
CASÂ
PubMedÂ
PubMed CentralÂ
Google ScholarÂ
WFO Plant List: https://wfoplantlist.org/plant-list/taxon/wfo-0000088383-2023-06?page=1 (accessed on 13 November 2023).Tropicos.org. Missouri Botanical Garden. Available online: https://www.tropicos.org (accessed on 13 November 2023).Jorgensen, P., Leon-Yanez, S. Catalogue of the Vascular Plants of Ecuador 309 (Missouri Botanical Garden Press, 1999).Hieronymus, G. H. Plantae peruvianae a claro Constantino de Jelski collectae. Compositae. Bot. Jahrb. Syst. 36, 505 (1905).
Google ScholarÂ
Adams, R. P. Identification of Essential Oil Components by Gas Chromatography/Mass Spectrometry 4th edn. (Allured Publishing Corporation, 2007).
Google ScholarÂ
Gancel, A.-L. et al. Leaf volatile compounds of six citrus somatic allotetraploid hybrids originating from various combinations of lime, lemon, citron, sweet orange, and grapefruit. J. Agric. Food Chem. 53(6), 2224–2230. https://doi.org/10.1021/jf048315b (2005).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Fernandez-Segovia, I., Escriche, I., Gomez-Sintes, M., Fuentes, A. & Serra, J. A. Influence of different preservation treatments on the volatile fraction of desalted cod. Food Chem. 98(3), 473–482. https://doi.org/10.1016/j.foodchem.2005.06.021 (2006).ArticleÂ
CASÂ
Google ScholarÂ
Duque, C., Bonilla, A., Bautista, E. & Zea, S. Exudation of low molecular weight compounds (thiobismethane, methyl isocyanide, and methyl isothiocyanate) as a possible chemical defense mechanism in the marine sponge Ircinia felix. Biochem. Syst. Ecol. 59(5), 459–467. https://doi.org/10.1016/S0305-1978(00)00081-8 (2001).ArticleÂ
Google ScholarÂ
Rega, B., Fournier, N., Nicklaus, S. & Guichard, E. Role of pulp in flavor release and sensory perception in orange juice. J. Agric. Food Chem. 52(12), 4204–4212. https://doi.org/10.1021/jf035361n (2004).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Vichi, S., Pizzale, L., Conte, L. S., Buxaderas, S. & López-Tamames, E. Solid-phase microextraction in the analysis of virgin olive oil volatile fraction: characterization of virgin olive oils from two distinct geographical areas of Northern Italy. J. Agric. Food Chem. 51(22), 6572–6577. https://doi.org/10.1021/jf030269c (2003).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Zheng, C. H., Kim, K. H., Kim, T. H. & Lee, H. J. Analysis and characterization of aroma-active compounds of Schizandra chinensis (omija) leaves. J. Sci. Food Agric. 85(1), 161–166. https://doi.org/10.1002/jsfa.1975 (2005).ArticleÂ
CASÂ
Google ScholarÂ
Mahajan, S. S., Goddik, L. & Qian, M. C. Aroma compounds in sweet why powder. J. Dairy Sci. 87(12), 4057–4063. https://doi.org/10.3168/jds.S0022-0302(04)73547-X (2004).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Kotseridis, Y. & Baumes, R. Identification of impact odorants in Bordeaux red grape juice, in the commercial yeast used for its fermentation, and in the produced wine. J. Agric. Food Chem. 48(2), 400–406. https://doi.org/10.1021/jf990565i (2000).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Chen, C.-C., Kuo, M.-C., Lui, S.-E. & Wu, C.-M. Volatile components of salted and pickled prunes (Prunus mume Sieb. et Zucc). J. Agric. Food Chem. 34(1), 140–144. https://doi.org/10.1021/jf00067a038 (1986).ArticleÂ
CASÂ
Google ScholarÂ
Vinogradov, B.A. Production, composition, properties and application of essential oils. http://viness.narod.ru (2004).Kim, T. H., Thuy, N. T., Shin, J. H., Beak, H. H. & Lee, H. J. Aroma-active compounds of miniature beefsteak plant (Mosla dianthera Maxim.). J. Agric. Food Chem. 48(7), 2877–2881. https://doi.org/10.1021/jf000219x (2000).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Paniandy, J.-C., Chane-Ming, J. & Pierbattesti, J.-C. Chemical composition of the essential oil and headspace solid-phase microextraction of the guava fruit (Psidium guajava L.). J. Essent. Oil Res. 22(12), 153–158. https://doi.org/10.1080/14786410802055568 (2000).ArticleÂ
CASÂ
Google ScholarÂ
Ferretti, G., Maggi, F. & Tirillini, B. Essential oil composition of Hypericum richeri Vill. from Italy. Flavour Fragr. J. 20(3), 295–398. https://doi.org/10.1002/ffj.1412 (2005).ArticleÂ
CASÂ
Google ScholarÂ
Bortolomeazzi, R., Berno, P., Pizzale, L. & Conte, L. S. Sesquiterpene, alkene, and alkane hydrocarbons in virgin olive oils of different varieties and geographical origins. J. Agric. Food Chem. 49(7), 3278–3283. https://doi.org/10.1021/jf001271w (2001).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Bendiabdellah, A. et al. Biological activities and volatile constituents of Daucus muricatus L. from Algeria. Chem. Centr. J. 6(48), 1–22. https://doi.org/10.1186/1752-153X-6-48 (2012).ArticleÂ
CASÂ
Google ScholarÂ
Ferhat, M. A., Meklati, B. Y. & Chemat, F. Comparison of different isolation methods of essential oil from Citrus fruits: Cold pressing, hydrodistillation and microwave dry distillation. Flavour Fragr. J. 22(6), 494–504. https://doi.org/10.1002/ffj.1829 (2007).ArticleÂ
CASÂ
Google ScholarÂ
Yu, E. J., Kim, T. H., Kim, K. H. & Lee, H. J. Characterization of aroma-active compounds of Abies nephrolepis (Khingan fir) needles using aroma extract dilution analysis. Flavour Fragr. J. 19(1), 74–79. https://doi.org/10.1002/ffj.1314 (2004).ArticleÂ
CASÂ
Google ScholarÂ
Baser, K. H. C., Özek, G., Özek, T., Duran, A. & Duman, H. Composition of the essential oils of Rhabdosciadium oligocarpum (Post ex Boiss.) Hedge et Lamond and Rhabdosciadium microcalycinum Hand. – Mazz. Flavour Fragr. J. 21(4), 650–655. https://doi.org/10.1002/ffj.1639 (2006).ArticleÂ
CASÂ
Google ScholarÂ
Merle, H., Verdeguer, M., Blázquez, M. A. & Boira, H. Chemical composition of the essential oils from Eriocephalus africanus L. var. Africanus populations growing in Spain. Flavour Fragr. J. 22(6), 461–464. https://doi.org/10.1002/ffj.1821 (2007).ArticleÂ
CASÂ
Google ScholarÂ
Vichi, S. et al. HS-SPME coupled to GC/MS for quality control of Juniperus communis L. berries used for gin aromatization. Food Chem. 105(4), 1748–1754. https://doi.org/10.1016/j.foodchem.2007.03.026 (2007).ArticleÂ
CASÂ
Google ScholarÂ
Hachicha, S. F., Skanji, T., Barrek, S., Ghrabi, Z. G. & Zarrouk, H. Composition of the essential oil of Teucrium ramosissimum Desf. (Lamiaceae) from Tunisia. Flavour Fragr. J. 22(2), 101–104. https://doi.org/10.1002/ffj.1764 (2007).ArticleÂ
CASÂ
Google ScholarÂ
Neves, A. et al. Screening of five essential oils for identification of potential inhibitors of IL-1-unduced Nf-kB activation and NO production in human clondrocytes: Characterization of the inhibitory activity of alpha-pinene. Plante Med. 76(03), 303–308. https://doi.org/10.1055/s-0029-1186085 (2010).ArticleÂ
CASÂ
Google ScholarÂ
Bendimerad, N. & Bendiab, S. A. T. Composition and antibacterial activity of Pseudocytisus integrifolius (Salisb.) essential oil from Algeria. J. Agric. Food Chem. 53(8), 2947–2952. https://doi.org/10.1021/jf047937u (2005).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Zaikin, V. G. & Borisov, R. S. Chromatographic-mass spectrometric analysis of Fishcer-Tropsch synthesis products. J. Anal. Chem. 57(6), 544–551 (2002).ArticleÂ
CASÂ
Google ScholarÂ
Mastelic, J., Jerkovic, I. & Mesic, M. Volatile constituents from flowers, leaves, bark and wood of Prunus mahaleb L.. Flavour Fragr. J. 21(2), 306–313. https://doi.org/10.1002/ffj.1596 (2006).ArticleÂ
CASÂ
Google ScholarÂ
Madruga, M. S., Arruda, S. G. B., Narain, N. & Souza, J. G. Castration and slaughter age effects on panel assessment and aroma compounds of the mestico goat meat. Meat Sci. 56(2), 117–125. https://doi.org/10.1016/S0309-1740(00)00025-5 (2000).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Choi, H.-S. Headspace analyses of fresh leaves and stems of Angelica gigas Nakai, a Korean medicinal herb. Flavour Fragr. J. 21(4), 604–608. https://doi.org/10.1002/ffj.1602 (2006).ArticleÂ
CASÂ
Google ScholarÂ
Condurso, C. et al. The leaf volatile constituents of Isatis tinctoria by solid phase microextraction and gas chromatography/mass spectrometry. Planta Med. 72(10), 924–928. https://doi.org/10.1055/s-2006-946679 (2006).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Utsunomia, H., Kawata, J., Chanoki, W., Shirakawa, N. & Miyazawa, M. Components of essential oil from woods of Prunus mume Sieb. at Zucc. J. Oleo Sci. 54(11), 609–612. https://doi.org/10.5650/jos.54.609 (2005).ArticleÂ
Google ScholarÂ
Radulovic, N., Blagojevic, P. & Palic, R. Comparative study of the leaf volatiles of Arctostaphylos uva-ursi (L.) Spreng and Vaccinium vitis-idaea L. (Ericaceae). Molecules 15(9), 6168–6185. https://doi.org/10.3390/molecules15096168 (2010).ArticleÂ
CASÂ
PubMedÂ
PubMed CentralÂ
Google ScholarÂ
Brenna, E., Fuganti, C. & Serra, S. Enantioselective perception of chiral odorants. Tetrahedron: Asymmetry 14, 1–42 (2003).ArticleÂ
CASÂ
Google ScholarÂ
Lis-Balcnin, M., Ochocka, R. J., Deans, S. G., Asztemborska, M. & Hart, S. Differences in bioactivity between the enantiomers of α-pinene. J. Essent. Oil Res. 11, 393–397 (1999).ArticleÂ
Google ScholarÂ
Nishida, R., Shelly, T. E., Whittier, T. S. & Kaneshiro, K. Y. α-Copaene, a potential rendezvous cue for the Mediterranean fruit fly, Ceratitis Capitata?. J. Chem Ecol. 26(1), 87–100. https://doi.org/10.1023/A:1005489411397 (2000).ArticleÂ
CASÂ
Google ScholarÂ
Dewick, P. M. Medicinal Natural Products. A Biosynthetic Approach 3rd edn. (John Wiley & Sons Ltd, 2009).BookÂ
Google ScholarÂ
Van Den Dool, H. & Kratz, P. D. A generalization of the retention index system including linear temperature programmed gas-liquid partition chromatography. J. Chromatogr. 11, 463–471 (1963).ArticleÂ
Google ScholarÂ
Gilardoni, G., Matute, Y. & RamÃrez, J. Chemical and enantioselective analysis of the leaf essential oil from Piper coruscans Kunth (Piperaceae), a costal and Amazonian native species of Ecuador. Plants 9, 791. https://doi.org/10.3390/plants9060791 (2020).ArticleÂ
CASÂ
PubMedÂ
PubMed CentralÂ
Google ScholarÂ
De Saint Laumer, J. Y., Cicchetti, E., Merle, P., Egger, J. & Chaintreau, A. Quantification in gas chromatography: prediction of flame ionization detector response factors from combustion enthalpies and molecular structures. Anal. Chem. 82, 6457–6462 (2010).ArticleÂ
PubMedÂ
Google ScholarÂ
Tissot, E., Rochat, S., Debonneville, C. & Chaintreau, A. Rapid GC-FID quantification technique without authentic samples using predicted response factors. Flavour Fragr. J. 27, 290–296 (2012).ArticleÂ
CASÂ
Google ScholarÂ