How does ferrocene correlate with ferroptosis? Multiple approaches to explore ferrocene-appended GPX4 inhibitors as anticancer agents

Chem. Sci., 2024, 15,10477-10490DOI: 10.1039/D4SC02002B, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Wei Li, Jing Yu, Jing Wang, Xuejing Fan, Ximing Xu, Hui Wang, Ying Xiong, Xinyu Li, Xiaomin Zhang, Qianer Zhang, Xin Qi, Pascal Pigeon, Qing Gu, Julia Bruno-Colmenarez, Gérard Jaouen, Michael J. McGlinchey, Xue Qiu, Shu-Li You, Jing Li, Yong WangFerrocene correlates with ferroptosis: multiple approaches to explore ferrocene-appended GPX4 inhibitors as dual-function ferroptosis inducers, which consummate the potential of ferrocene in ferroptosis-targeted drug development.The content of this RSS Feed (c) The Royal Society of Chemistry