Horne, W. S. & Grossmann, T. N. Proteomimetics as protein-inspired scaffolds with defined tertiary folding patterns. Nat. Chem. 12, 331–337 (2020).ArticleÂ
CASÂ
PubMedÂ
PubMed CentralÂ
Google ScholarÂ
Holtkamp, W. et al. Cotranslational protein folding on the ribosome monitored in real time. Science 350, 1104–1107 (2015).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Tsuboyama, K. et al. Mega-scale experimental analysis of protein folding stability in biology and design. Nature 620, 434–444 (2023).ArticleÂ
CASÂ
PubMedÂ
PubMed CentralÂ
Google ScholarÂ
Hartl, F. U. & Hayer-Hartl, M. Molecular chaperones in the cytosol: from nascent chain to folded protein. Science 295, 1852–1858 (2002).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Hartl, F. U., Bracher, A. & Hayer-Hartl, M. Molecular chaperones in protein folding and proteostasis. Nature 475, 324–332 (2011).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Balchin, D., Hayer-Hartl, M. & Hartl, F. U. In vivo aspects of protein folding and quality control. Science 353, aac4354 (2016).ArticleÂ
PubMedÂ
Google ScholarÂ
Shoulders, M. D. & Raines, R. T. Collagen structure and stability. Annu. Rev. Biochem. 78, 929–958 (2009).ArticleÂ
CASÂ
PubMedÂ
PubMed CentralÂ
Google ScholarÂ
Fu, L. et al. Cartilage-like protein hydrogels engineered via entanglement. Nature 618, 740–747 (2023).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Mittelheisser, V. et al. Evidence and therapeutic implications of biomechanically regulated immunosurveillance in cancer and other diseases. Nat. Nanotechnol. 19, 281–297 (2024).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Infante, E. et al. The mechanical stability of proteins regulates their translocation rate into the cell nucleus. Nat. Phys. 15, 973–981 (2019).ArticleÂ
CASÂ
PubMedÂ
PubMed CentralÂ
Google ScholarÂ
Jamieson, E. M. G., Modicom, F. & Goldup, S. M. Chirality in rotaxanes and catenanes. Chem. Soc. Rev. 47, 5266–5311 (2018).ArticleÂ
CASÂ
PubMedÂ
PubMed CentralÂ
Google ScholarÂ
Wasserman, E. The preparation of interlocking rings: a catenane. J. Am. Chem. Soc. 82, 4433–4434 (1960).ArticleÂ
CASÂ
Google ScholarÂ
May, J. H. et al. Active template strategy for the preparation of Ï€-conjugated interlocked nanocarbons. Nat. Chem. 15, 170–176 (2023).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Benke, B. P. et al. Dimeric and trimeric catenation of giant chiral [8 + 12] imine cubes driven by weak supramolecular interactions. Nat. Chem. 15, 413–423 (2023).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Cui, Z. & Jin, G.-X. Construction of a molecular prime link by interlocking two trefoil knots. Nat. Synth. 1, 635–640 (2022).ArticleÂ
Google ScholarÂ
Zhang, L. et al. An electric molecular motor. Nature 613, 280–286 (2023).ArticleÂ
CASÂ
PubMedÂ
PubMed CentralÂ
Google ScholarÂ
Zhang, L. et al. Stereoselective synthesis of a composite knot with nine crossings. Nat. Chem. 10, 1083–1088 (2018).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Leigh, D. A. et al. Tying different knots in a molecular strand. Nature 584, 562–568 (2020).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Inomata, Y., Sawada, T. & Fujita, M. Metal–peptide torus knots from flexible short peptides. Chem 6, 294–303 (2020).ArticleÂ
CASÂ
Google ScholarÂ
Garci, A. et al. Mechanically interlocked pyrene-based photocatalysts. Nat. Catal. 5, 524–533 (2022).ArticleÂ
CASÂ
Google ScholarÂ
Mitra, R., Zhu, H., Grimme, S. & Niemeyer, J. Functional mechanically interlocked molecules: asymmetric organocatalysis with a catenated bifunctional brønsted acid. Angew. Chem. Int. Ed. 56, 11456–11459 (2017).ArticleÂ
CASÂ
Google ScholarÂ
Ronson, T. K. et al. An S10-symmetric 5-fold interlocked [2]catenane. J. Am. Chem. Soc. 142, 10267–10272 (2020).ArticleÂ
CASÂ
PubMedÂ
PubMed CentralÂ
Google ScholarÂ
Gao, X. et al. Synthesis and near-infrared photothermal conversion of discrete supramolecular topologies featuring half-sandwich [Cp*Rh] units. J. Am. Chem. Soc. 143, 17833–17842 (2021).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Yu, H. M. et al. Self-assembly of cluster-mediated 3D catenanes with size-specific recognition behavior. J. Am. Chem. Soc. 145, 25103–25108 (2023).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Forgan, R. S., Sauvage, J.-P. & Stoddart, J. F. Chemical topology: complex molecular knots, links, and entanglements. Chem. Rev. 111, 5434–5464 (2011).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Gao, W. X. et al. Coordination-directed construction of molecular links. Chem. Rev. 120, 6288–6325 (2020).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Zhang, Z. H. et al. Molecular weaving. Nat. Mater. 21, 275–283 (2022).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Agam, G., Graiver, D. & Zilkha, A. Studies on the formation of topological isomers by statistical methods. J. Am. Chem. Soc. 98, 5206–5214 (1976).ArticleÂ
CASÂ
Google ScholarÂ
Rocklin, G. J. et al. Global analysis of protein folding using massively parallel design, synthesis, and testing. Science 357, 168–175 (2017).ArticleÂ
CASÂ
PubMedÂ
PubMed CentralÂ
Google ScholarÂ
Rosengren, K. J. et al. Microcin J25 has a threaded sidechain-to-backbone ring structure and not a head-to-tail cyclized backbone. J. Am. Chem. Soc. 125, 12464–12474 (2003).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Cook, T. R. & Stang, P. J. Recent developments in the preparation and chemistry of metallacycles and metallacages via coordination. Chem. Rev. 115, 7001–7045 (2015).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Yamashina, M. et al. An antiaromatic-walled nanospace. Nature 574, 511–515 (2019).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Fujita, D. et al. Self-assembly of tetravalent Goldberg polyhedra from 144 small components. Nature 540, 563–566 (2016).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Wu, K., Benchimol, E., Baksi, A. & Clever, G. H. Non-statistical assembly of multicomponent [Pd2ABCD] cages. Nat. Chem. 16, 584–591 (2024).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Rabone, J. et al. An adaptable peptide-based porous material. Science 329, 1053–1057 (2010).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Katsoulidis, A. P. et al. Chemical control of structure and guest uptake by a conformationally mobile porous material. Nature 565, 213–217 (2019).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Misra, R., Saseendran, A., Dey, S. & Gopi, H. N. Metal-helix frameworks from short hybrid peptide foldamers. Angew. Chem. Int. Ed. 58, 2251–2255 (2019).ArticleÂ
CASÂ
Google ScholarÂ
Jeong, S. et al. Conformational adaptation of β-peptide foldamers for the formation of metal–peptide frameworks. Angew. Chem. Int. Ed. 61, e202108364 (2022).ArticleÂ
CASÂ
Google ScholarÂ
Lv, S. et al. Designed biomaterials to mimic the mechanical properties of muscles. Nature 465, 69–73 (2010).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Elvin, C. M. et al. Synthesis and properties of crosslinked recombinant pro-resilin. Nature 437, 999–1002 (2005).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Bartlett, A. I. & Radford, S. E. An expanding arsenal of experimental methods yields an explosion of insights into protein folding mechanisms. Nat. Struct. Mol. Biol. 16, 582–588 (2009).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Dong, J. et al. Free-standing homochiral 2D monolayers by exfoliation of molecular crystals. Nature 602, 606–611 (2022).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Jiao, J. et al. Design and assembly of chiral coordination cages for asymmetric sequential reactions. J. Am. Chem. Soc. 140, 2251–2259 (2018).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Dong, J., Liu, Y. & Cui, Y. Supramolecular chirality in metal–organic complexes. Acc. Chem. Res. 54, 194–206 (2021).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Mossing, M. C. & Sauer, R. T. Stable, monomeric variants of λ Cro obtained by insertion of a designed β-hairpin sequence. Science 250, 1712–1715 (1990).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Meng, W. et al. An elastic metal–organic crystal with a densely catenated backbone. Nature 598, 298–303 (2021).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
August, D. P. et al. Self-assembly of a layered two-dimensional molecularly woven fabric. Nature 588, 429–435 (2020).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Liu, Y. et al. Weaving of organic threads into a crystalline covalent organic framework. Science 351, 365–369 (2016).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Hu, Y. et al. Single crystals of mechanically entwined helical covalent polymers. Nat. Chem. 13, 660–665 (2021).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Bera, S. et al. Rigid helical-like assemblies from a self-aggregating tripeptide. Nat. Mater. 18, 503–509 (2019).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Adler-Abramovich, L. et al. Self-assembled organic nanostructures with metallic-like stiffness. Angew. Chem. Int. Ed. 49, 9939–9942 (2010).ArticleÂ
CASÂ
Google ScholarÂ
Knowles, T. P. J. & Buehler, M. J. Nanomechanics of functional and pathological amyloid materials. Nat. Nanotechnol. 6, 469–479 (2011).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ
Ge, M. et al. Vancomycin derivatives that inhibit peptidoglycan biosynthesis without binding d-Ala–d-Ala. Science 284, 507–511 (1999).ArticleÂ
CASÂ
PubMedÂ
Google ScholarÂ