A pioneering new DNA forensics technique is looking for a reliable method to measure a suspect’s individual level of natural shedding of skin and other cells to add to, and compare with, evidence collected at crime scenes. Using a novel technique of cell staining developed at Flinders University, forensic science experts have tested 100 people to confirm how people shed varying levels of touch DNA, from very low to very high.
Journal/conference: Forensic Science International: Genetics
Link to research (DOI): Paper
Organisation/s: Flinders University
Funder: This work was supported by Forensic Science SA and the Ross Vining Memorial Research Fund.
Media release
From: Flinders University
A pioneering new DNA forensics technique is looking for a reliable method to measure a suspect’s individual level of natural shedding of skin and other cells to add to, and compare with, evidence collected at crime scenes.Using a novel technique of cell staining developed at Flinders University, forensic science experts have tested 100 people to confirm how people shed varying levels of touch DNA, from very low to very high.“Our latest study also shows that males are more prolific shedding in general, depositing more cells per square millimetre than females,” says Professor Adrian Linacre, from the College of Science and Engineering.“Also there was no difference in the deposition of cells between right and left thumbs, so it doesn’t matter if an item is held in someone’s right or left hand.”The study stems from a pilot study three years ago, and aims to develop a new avenue to track down criminals – including evidence from people who might be ‘poor shedders’.Professor Linacre says suspects implicated by DNA in a criminal act might one day raise the defence: “But I am a high shedder.”Of 100 donors in the study, 98 gave consistent and reproducible cell number deposition – showing people shed the same cells ‘no matter when’ samples are taken.The new study makes progress to develop a robust, simple and affordable test of a suspected perpetrators’ ‘shedder status’ as an additional means of DNA profiling and testing the possible time spent at a crime scene. This potentially could be a way to reduce investigation timeframes, and reduce the possibility of conflicting DNA evidence.“Depending on what type of ‘shedder’ a person is, confirmation of their shedder status can guide investigators as to the propensity of an individual to pass on their DNA to an item via touch contact with the hand.“This information can be used in a likelihood ratio to evaluate the probability of finding a person’s DNA on an item,” Professor Linacre explains.Researchers stress more needs to be done to find the best way to assess shedder status.The latest research to widen the shedder experiments was conceptualised by Flinders PhD Dr Piyamas (Kanokwongnuwut) Petcharoen and received funding from the Attorney-General’s Department through Forensic Science SA and the Ross Vining Memorial Research Fund.Dr Petcharoen, now based at the Suranaree University of Technology in Thailand, is a coauthor of the new study published in Forensic Science International: Genetics, along with Flinders University colleagues Madison Nolan, Professor Paul Kirkbride and Professor Linacre.The article, Shedding more light on shedders (2024) by Piyamas Petcharoen, Madison Nolan, K. Paul Kirkbride and Adrian Linacre has been published in Forensic Science International: Genetics. DOI: 10.1016/j.fsigen.2024.103065