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Regionally enriched rare deleterious exonic variants in the UK and Ireland

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Based on the regional availability of participants with WES data in UKB we classified samples into 16 geographical regions of origin (Methods). These regions...
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Inferring replication timing and proliferation dynamics from single-cell DNA sequencing data

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PERT modelThe input for PERT is scWGS read depth (Z) and called CN states for all bins (N cells  ×  M loci) (Fig. S1a). Input CN...
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scientists impressed by latest ChatGPT model o1

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Long-term tracking of social structure in groups of rats

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Long-term tracking and quantifying individual behaviorWe tagged individuals with color markers and employed automated tracking to determine each rat’s movement over time (Fig. 1A–D)....
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A phenocopy signature of TP53 loss predicts response to chemotherapy

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Levine, A. J. p53: 800 million years of evolution and 40 years of discovery. Nat. Rev. Cancer 20, 471–480 (2020).Article  CAS  ...
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