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Prediction of protein secondary structure by the improved TCN-BiLSTM-MHA model with knowledge distillation

Evaluation metricsIn this article, three primary evaluation metrics were used to assess the performance of our protein secondary structure prediction models: the segment overlap...

SwitchFinder – a systematic search for RNA structural switches across the human transcriptome

RNA structural switches play crucial roles in regulating gene expression, particularly in bacteria, but their study in more complex organisms like humans has been...

scSemiProfiler: Advancing large-scale single-cell studies through semi-profiling with deep generative models and active learning

Method overviewThe scSemiProfiler approach represents a deep neural network framework for decomposing broad-scope bulk sequencing data into detailed single-cell cohorts. It achieves this by...

CGMega: explainable graph neural network framework with attention mechanisms for cancer gene module dissection

Overview of CGMega frameworkWe proposed a new framework, CGMega, for studying cancer gene modules based on graph attention and graph interpretation technologies (Fig. 1a). CGMega...

Systematic analysis of microorganisms’ metabolism for selective targeting

Hill, C. Microbiome and infection: A case for “selective depletion”. Ann. Nutr. Metab. 77(3), 4–9 (2021).Article  CAS  ...

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