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Low-level brain somatic mutations in exonic regions are collectively implicated in autism with germline mutations in autism risk genes

De Rubeis, S. & Buxbaum, J. D. Genetics and genomics of autism spectrum disorder: embracing complexity. Hum. Mol .Genet. 24, R24–R31 (2015).Article  ...

Featured RNA-Seq Job – Associate Scientist I (Sequencing)

in Jobs 18 mins ago 10 Views The New York Genome Center is looking for a highly motivated, independent but team-oriented Associate Scientist I...

Neutrophil extracellular traps mediate the crosstalk between plaque microenvironment and unstable carotid plaque formation

Bioinformatics analysisIn this study, we downloaded the raw gene expression data from the GSE28829, GSE41571, GSE43292, GSE179828, GSE145200, and GSE3037 datasets obtained from the...

Deep learning prediction of glycopeptide tandem mass spectra powers glycoproteomics

Wang, Y. C., Peterson, S. E. & Loring, J. F. Protein post-translational modifications and regulation of pluripotency in human stem cells. Cell Res. 24,...

Neural network extrapolation to distant regions of the protein fitness landscape

Neural network model trainingWe used the Olson et al. GB1-IgG binding dataset20 and the Gelman et al. model architectures12 with the same parameter initializations,...

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