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AI-powered omics-based drug pair discovery for pyroptosis therapy targeting triple-negative breast cancer

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Ethical statementAll the animal experiments were performed in accordance with the guidelines evaluated and approved by Institutional Animal Care and Use Committee (IACUC), Fudan...
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Unveiling disulfidptosis-related biomarkers and predicting drugs in Alzheimer’s disease

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De-Paula, V. J., Radanovic, M., Diniz, B. S. & Forlenza, O. V. Alzheimer’s disease. Subcell. Biochem. 65, 329–352 (2012).Article  CAS  ...
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Time-series sewage metagenomics distinguishes seasonal, human-derived and environmental microbial communities potentially allowing source-attributed surveillance

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Abundance and diversity of recovered genomesMetagenomic assemblies of all the individual samples resulted in 42,731,574 contigs with an average length of 2179 bp (N50: 2303)...
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Genomic insights on carotenoid synthesis by extremely halophilic archaea Haloarcula rubripromontorii BS2, Haloferax lucentense BBK2 and Halogeometricum borinquense E3 isolated from the solar salterns...

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Oren, A. Halophilic microbial communities and their environments. Curr. Opin. Biotechnol. 33, 119–124. https://doi.org/10.1016/j.copbio.2015.02.005 (2015).Article  CAS  PubMed  ...
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CNVDeep: deep association of copy number variants with neurocognitive disorders | BMC Bioinformatics

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Associations of the regions with the target disordersOur model was trained using ~ 195,500 CNVs from patients and healthy individuals (nearly 60 percent from patients and...
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