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Convergent evolution of plant prickles by repeated gene co-option over deep time | Science

An enduring question in evolutionary biology concerns the degree to which episodes of convergent trait evolution depend on the same genetic programs, particularly over...

Mechanism of PCNA loading by Ctf18-RFC for leading-strand DNA synthesis | Science

The proliferating cell nuclear antigen (PCNA) clamp encircles DNA to hold DNA polymerases (Pols) to DNA for processivity. The Ctf18-RFC PCNA loader, a replication...

A chemogenetic screen reveals that Trpv1-expressing neurons control regulatory T cells in the gut | Science

Neuroimmune cross-talk participates in intestinal tissue homeostasis and host defense. However, the matrix of interactions between arrays of molecularly defined neuron subsets and of...

Letters: August 2024

Readers share their connections to the Flixborough disaster, discuss the importance of inorganic neurochemistry and more

Weight-loss drugmakers bet billions on boosting supplies | News

There is a gush of investment from drugmakers Eli Lilly and Novo Nordisk as the companies hasten to boost production of their new anti-obesity...

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