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Comparison of DNA methylation based classification models for precision diagnostics of central nervous system tumors

Patient materialFFPE or frozen tumor samples representing pediatric patient samples encountered on the typical pathology service were evaluated. The samples represented 650 samples expected...

Development of a polygenic score predicting drug resistance and patient outcome in breast cancer

Discovery pipeline for identification of expression biomarkers associated with drug responseTo systematically discover the biomarkers that are predictive of anti-cancer drug response we followed...

An optimized instrument variable selection approach to improve causality estimation in association studies

We demonstrate the robustness of our proposed pipeline using five different MR datasets. Overall, the results of these datasets revealed an improvement in the...

Retinol semisolid preparations in cosmetics: transcutaneous permeation mechanism and behaviour

Members of the vitamin A family, include retinoic acid, retinol esters and retinol, are widely used in cosmetics and pharmaceuticals. Especially retinol is relatively...

Retinal fundus image super-resolution based on generative adversarial network guided with vascular structure prior

Due to the superior image generation capability of generative adversarial networks, it can be applied to improve the quality of retinal fundus imaging to...

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