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DNA polymerase ε produces elevated C-to-T mutations at methylated CpG dinucleotides

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.This is a summary of: Tomkova, M. et...

Enhancing fairness in AI-enabled medical systems with the attribute neutral framework

DatasetsIn this study, we include three large-scale public chest X-ray datasets, namely ChestX-ray1415, MIMIC-CXR16, and CheXpert17. The ChestX-ray14 dataset comprises 112,120 frontal-view chest X-ray...

Polygenic risk and rare variant gene clustering enhance cancer risk stratification for breast and prostate cancers

Disease risk can be stratified according to PRS in conjunction with monogenic variants in high-risk genes11,13,21. Using the EPRS approach, we systematically categorized monogenic...

Integrating Kalman filter noise residue into U-Net for robust image denoising: the KU-Net model

In the field of image processing, the U-Net architecture has grown to be indispensable, especially for tasks like segmentation, denoising, and restoration. U-Net was...

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