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Unlocking the power of nanopores

Transmembrane β-barrel pores (TMBs) are extensively used for single-molecule DNA and RNA sequencing. They enable the miniaturization of a wide array of sensing and...

A single-cell pan-cancer analysis to show the variability of tumor-infiltrating myeloid cells in immune checkpoint blockade

TIM landscape varies significantly among cancer types and treatment groupsTo begin assessing TIM heterogeneity across cancers, we conducted scRNA-seq on tumor samples from 129...

Copy number losses of oncogenes and gains of tumor suppressor genes generate common driver mutations

A statistical method to test interaction between somatic selection on mutations and CNA in genesWe sought to rigorously measure somatic selection associated with a...

Development and external validation of a predictive model for type 2 diabetic retinopathy

Building on our previous study, the present study innovatively developed a DR risk prediction model that integrates five key variables: Neutrophil, 25(OH)D3, Duration of...

A panel sequencing dataset of peripheral blood gene variations in pan-cancer

Tao, Z. et al. Characterizations of Cancer Gene Mutations in Chinese Metastatic Breast Cancer Patients. Front Oncol 10, 1023 (2020).Article  PubMed  ...

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