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Adding metabolic tasks to human GEM models to improve the study of gene targets and their associated toxicities

Genomic-scale metabolic modelsA metabolic network can be represented as a triplet (M, R, S) consisting of sets of metabolites (M) and reactions (R). If the network...

Norms prioritizing positive assessments are likely to maintain cooperation in private indirect reciprocity

Agent-based model of social dilemma gamesWe construct an agent-based model here. Consider a well-mixed finite group of N individuals playing social dilemma games. In...

High expression of YEATS2 as a predictive factor of poor prognosis in patients with hepatocellular carcinoma

Expression of YEATS2 in HCC by the databaseThe obtained results of this study demonstrated that HCC tissues had an elevated level of YEATS2 expression...

Unravelling the origins and forces that shape mtDNA mutations in human cells

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.This is a summary of: An, J. et...

AI-guided few-shot inverse design of HDP-mimicking polymers against drug-resistant bacteria

Data preprocessingWe made same data preprocessing to all the antibacterial activity data including MIC values as well as HC10 values. If the end point...

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