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Stopped clinical trials give evidence for the value of genetics

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Plenge, R. et al. Nat. Rev. Drug Discov. 12, 581–594 (2013).Article  PubMed  CAS  ...
HEALTHY

‘Gene misbehaviour’ widespread in healthy population

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NIHR Cambridge BRC researchers have been involved in a major study published this week in the American Journal of Human Genetics that shows that...
HEALTHY

lncRNA signature mediates mitochondrial permeability transition-driven necrosis in regulating the tumor immune microenvironment of cervical cancer

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The weighted gene co-expression network analysis of the CESC differential genesThrough the differential analysis of the RNA-seq data of the 309 cervical tissue samples,...
HEALTHY

A network-based trans-omics approach for predicting synergistic drug combinations

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Construction of the human molecular interaction networkHuman molecular interactions were constructed from seven databases (Supplementary Data S1): (i) Yeast-two-hybrid high-throughput datasets were retrieved from the...
HEALTHY

In silico molecular screening of bioactive natural compounds of rosemary essential oil and extracts for pharmacological potentials against rhinoviruses

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Structural identification and properties of the RV capsid proteinThe obtained 3D structure of the RV capsid protein had four chains (chain1, chain2, chain3, and...
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