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BEROLECMI: a novel prediction method to infer circRNA-miRNA interaction from the role definition of molecular attributes and biological networks | BMC Bioinformatics

Evaluation criteriaIn this study, we introduce five-fold cross-validation (five-fold CV) to evaluate the performance of the proposed method. five-fold CV divides the CMI data...

Comparative analysis of feature selection techniques for COVID-19 dataset

4778 COVID-19 patients were included in the study, which examined 116 routine clinical, laboratory, and demographic features. The fatality rate in this cohort was...

De novo generation of SARS-CoV-2 antibody CDRH3 with a pre-trained generative large language model

The framework of PALM-H3 and A2BinderThe workflow and model framework of the PALM-H3 and A2binder are shown in Fig. 1. The purpose of PALM-H3 is...

CHD4 R975H mutant activates tumorigenic pathways and promotes stemness and M2-like macrophage polarization in endometrial cancer

CHD4 mutation occurs frequently in endometrial cancerThe frequency of CHD4 mutations in endometrial cancer was systematically investigated by analysing data from various databases associated...

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