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Coassembly and binning of a twenty-year metagenomic time-series from Lake Mendota

Sample collection and DNA extractionSamples collected from Lake Mendota were obtained through the NTL-LTER program (https://lter.limnology.wisc.edu/). Sample collection and DNA extraction, but not shotgun...

Large-scale analysis of whole genome sequencing data from formalin-fixed paraffin-embedded cancer specimens demonstrates preservation of clinical utility

We examined a cohort comprising 578 WGS FFPE-stored treatment naïve primary cancer samples from nine tumour-types and matched germline samples derived from peripheral blood...

AutoFocus: a hierarchical framework to explore multi-omic disease associations spanning multiple scales of biomolecular interaction

Description of AutoFocus frameworkThe AutoFocus tool enables fast clustering and phenotype association of multiple omics datasets, accompanied by an intuitive, interactive application for result...

Teaching old docks new tricks with machine learning enhanced ensemble docking

Methodological detailsInput format and optionsAs input, EnOpt accepts a CSV-formatted (n times m) matrix of docking scores, organized as a set of n compounds...

An encryption algorithm for color images based on an improved dual-chaotic system combined with DNA encoding

Experiments were conducted on a PC equipped with an Intel® Core™ i7-12650H CPU operating at 2.30 GHz, 16 GB of memory, and a 64-bit Windows 11...

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