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starTracer is an accelerated approach for precise marker gene identification in single-cell RNA-Seq analysis

Rationale of starTracerSingle-cell sequencing data includes an expression matrix and an annotation matrix (Fig. 7A). The previous strategy for identifying marker genes within a cluster...

The global geography of artificial intelligence in life science research

Dimension one: productivityWe begin our assessment of productivity by documenting an exponential increase in global AI life science publications (Fig. 1), quantified by a 20%...

DAMM for the detection and tracking of multiple animals within complex social and environmental settings

Object detection approachWe employed the Mask R-CNN architecture for instance segmentation, which detects individual objects within an image and delineates each object’s precise location...

Tipping-point transition from transient to persistent inflammation in pancreatic islets

Mapping known IL-1 regulations to a mathematical modelIn order to minimize the number of unknown parameters and variables, we aimed to construct a simple...

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