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Multistate and functional protein design using RoseTTAFold sequence space diffusion

Sequence representationTo apply the diffusion framework in sequence space, a continuous representation of the categorical sequence data is needed. To implement this, we represented...

Statistical method reveals new insights into single-cell RNA sequencing

A new statistical technique developed by a researcher at the Texas A&M University School of Public Health and colleagues elsewhere offers fresh insights into...

A simpler, easier way to analyze Multiomic Data

Multiomics is revolutionizing research and pushing the limits of scientific discovery. There are many ways to combine multiple “-omes” into one experiment, but all...

Joint inference of discrete cell types and continuous type-specific variability in single-cell datasets with MMIDAS

Fishell, G. & Heintz, N. The neuron identity problem: form meets function. Neuron 80, 602–612 (2013).Article  ...

Expanding the genome editing toolbox with designer CRISPR–Cas-like transposons

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.This is a summary of: Marquart, K. F....

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